Research interests
Recent studies have surprisingly shown that the majority of memory T cells do not reside in lymphoid organs but rather in various non-lymphoid organs (NLT) such as the skin, intestines and liver. These tissue-resident memory T cells (TRM) act as sentinels for pathogens, interact with parenchyma and microbiota and maintain normal tissue function. Many of the requirements for TRM generation – both cell-intrinsic and niche-related – are still unknown. In my PhD project, I aim to elucidate the transcriptional networks and cellular processes that control TRM generation, persistence and function.
