Research interests
ELAV family proteins are crucial for the maturation of neuronal cells. ELAV proteins primarily achieve this task due to their direct role in alternative polyadenylation, splicing and mRNA stability. ELAV itself is essential for the survival and development of D. melanogaster, and its deletion leads to embryonic lethality. In order to maintain normal ELAV function, its protein levels need to be tightly regulated. Previous studies have suggested ELAV's role in the regulation of its own protein production. However, the mechanism involved in this regulation of ELAV production remains uriknown. In my PhD project, I aim to delineate the mechanism for this translational regulation that ensures ELAV function.
