Publications

Altas, B.; Rhee, H.-J.; Ju, A.; Solís, H. C.; Karaca, S.; Winchenbach, J.; Kaplan-Arabaci, O.; Schwark, M.; Ambrozkiewicz, M. C.; Lee, C. et al.; Spieth, L.; Wieser, G. L.; Chaugule, V. K.; Majoul, I.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Koganezawa, N.; Hanamura, K.; Rotin, D.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Poulopoulos, A.; Urlaub, H.; Jahn, O.; Saher, G.; Brose, N.; Rhee, J.; Kawabe, H.: Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 223, e201902050 (2023)

Antonio Urrutia, G.; Ramachandran, H.; Cauchy, P.; Boo, K.; Ramamoorthy, S.; Boller, S.; Dogan, E.; Clapes, T.; Trompouki, E.; Torres-Padilla, M.-E. et al.; Palvimo, J. J.; Pichler, A.; Grosschedl, R.: ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation. Genes and Development 35, pp. 1143 - 1160 (2021)

Rawat, P.; Boehning, M.; Hummel, B.; Aprile-Garcia, F.; Pandit, A. S.; Eisenhardt, N.; Khavaran, A.; Niskanen, E.; Vos, S. M.; Palvimo, J. J. et al.; Pichler, A.; Cramer, P.; Sawarkar, R.: Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular Cell 81, pp. 1013 - 1026 (2021)

Böckelmann, L. C.; Basu, T.; Gründer, A.; Wang, W.; Breucker, J.; Kaiser, S.; Pichler, A.; Pahl, H. L.: Concomitant constitutive LNK and NFE2 mutation with loss of sum9oylation in a case of hereditary thrombocythemia. Haematologica (2020)

Breucker , J.; Pichler, A.: Analysis of Sumoylation. Methods in Molecular Biology 1934, pp. 223 - 233 (2019)

Eisenhardt, N.; Ilic, D.; Nagamalleswari, E.; Pichler, A.: Biochemical characterization of SUMO-conjugating enzymes by in vitro sumoylation assays. Methods in Enzymology 618, pp. 167 - 185 (2019)

Pichler, A.: How DNA vicinity controls SUMO E3 ligase activity. EMBO Journal, p. e99705 (2018)

Pichler, A.; Polychronis, F.; Lee, H.; Eisenhardt, N.: SUMO Conjugation - a mechanistic view. Biomolecular Concepts 8, pp. 13 - 36 (2017)

Koidl, S.; Eisenhardt, N.; Fatouros, C.; Droescher, M.; Chaugule, V. K.; Pichler, A.: The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability. The International Journal of Biochemistry & Cell Biology 79, pp. 478 - 487 (2016)

Tortola, L.; Nitsch, R.; Bertrand, M. J. M.; Kogler, M.; Redouane, Y.; Kozieradzki, I.; Uribesalgo, I.; Fennell, L. M.; Daugaard, M.; Klug, H. et al.; Wirnsberger, G.; Wimmer, R.; Perlot, T.; Sarao, R.; Rao, S.; Hanada, T.; Takahashi, N.; Kernbauer, E.; Demiröz, D.; Lang, M.; Superti-Furga, G.; Decker, T.; Pichler, A.; Ikeda, F.; Kroemer, G.; Vandenabeele, P.; Sorensen, P. H.; Penninger, J. M.: The Tumor Suppressor Hace1 is a Critical Regulator of TNFR1-mediated Cell Fate. Cell Reports 15, pp. 1481 - 1492 (2016)

Cappadocia, L.; Pichler, A.; Lima, C. D.: Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase. Nature Structural & Molecular Biology 22 (12), pp. 968 - 975 (2015)

Eisenhardt, N.; Chaugule, V. K.; Koidl, S.; Droescher, M.; Dogan, E.; Rettich, J.; Sutinen, P.; Imanishi, S. Y.; Hofmann, K.; Palvimo, J. J. et al.; Pichler, A.: A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly. Nature Structural Molecular & Biology 22 (12), pp. 959 - 967 (2015)

Klug, H.; Xaver, M.; Chaugule, V. K.; Koidl, S.; Mittler, G.; Klein, F.; Pichler, A.: Ubc9 Sumoylation Controls SUMO Chain Formation and Meiotic Synapsis in Saccharomyces cerevisiae. Molecular Cell 50, pp. 625 - 636 (2013)

Droescher, M.; Chaugule, V. K.; Pichler, A.: SUMO Rules: Regulatory Concepts and Their Implication in Neurologic Functions. Neuromolecular Medicine 15, pp. 639 - 660 (2013)

Knipscheer, P.; Klug, H.; Sixma, T.K.; Pichler, A.: Preparation of Sumoylated Substrates for Biochemical Analysis. Methods in Molecular Biology 497, pp. 201 - 210 (2009)

Pichler, A.: A second E2 for nedd8ylation expands substrate selection. Structure 17, pp. 321 - 322 (2009)

Pichler, A.: Analysis of Sumoylation. Methods in Molecular Biology 446, pp. 131 - 138 (2008)

Sachdev, S.; Bruhn, L.; Sieber, H.; Pichler, A.; Melchior, F.; Grosschedl, R.: PIASy, a nucler matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes and Development 15, pp. 3088 - 3103 (2001)

Gast, A.; Pichler, A.; Swaminathan, S.; Melchoir, F.: SUMO shofts to new functions. The ELSO Gazette 1 (2000)

Eisenhardt, N.; Chaugule, V.; Pichler, A.: A Fluorescent In Vitro Assay to Investigate Paralog-Specific SUMO Conjugation. In: Methods in Molecular Biology, Vol. 1475, pp. 67 - 78. Springer + Business, New York (2016)

Maderböck, K.; Pichler, A.: SUMO CONTROL. In: Conjugation and Deconjugation of Ubiquitin Family Modifiers, pp. 158 - 169 (Eds. Groettrup, M.; Landes Bioscience). Landes Bioscience, USA (2010)

Melchoir, F.; Pichler, A.: SUMO Modification. In: Encyclopedia of Biological Chemistry, Vol. 4, pp. 130 - 144 (2004)

Pichler, A.: Regulation of Sumo Conjugation. Habilitation, University of Vienna, Vienna (2010)