
Publications of Thomas Jenuwein
All genres
Journal Article (42)
2024
Journal Article
15, 3880 (2024)
MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation. Nature Communications 2023
Journal Article
30, pp. 489 - 501 (2023)
Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis. Nature Structural and Molecular Biology 2022
Journal Article
610, pp. 555 - 561 (2022)
An LKB1-mitochondria axis controls TH17 effector function. Nature 2021
Journal Article
12, 4359 (2021)
Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nature Communications
Journal Article
14, 166 (2021)
Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia. BMC Medical Genomics
Journal Article
49, pp. 5568 - 5587 (2021)
m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin. Nucleic Acids Research (London) 2020
Journal Article
53, pp. 934 - 951 (2020)
Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the emergence of Hematopoietic Stem and Progenitor Cells. Immunity
Journal Article
22, pp. 767 - 778 (2020)
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3. Nature Cell Biology
Journal Article
117, pp. 14251 - 14258 (2020)
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
129, pp. 83 - 98 (2020)
Heterochromatin formation in Drosophila requires genome-wide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryogenesis. Chromosoma: Biology of the Nucleus 2019
Journal Article
27, pp. 2063 - 2074 (2019)
Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Reports
Journal Article
363, pp. 294 - 297 (2019)
H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science 2018
Journal Article
9, 101 (2018) (2018)
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-kappa B pathway. Nature Communications 2017
Journal Article
40, pp. 383 - 391 (2017)
Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. European Heart Journal
Journal Article
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome assocation and RNA:DNA hybrid formation. eLife, p. e25293 (2017)
Journal Article
65, pp. 1904 - 1919 (2017)
The Histone Methyltransferase Suv39h2 Contributes to Nonalcoholic Steatohepatitis in Mice. Hepatology
Journal Article
18, pp. 914 - 928 (2017)
The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats. EMBO Reports
Journal Article
8, 14941 (2017) (2017)
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction. Nature Communications 2016
Journal Article
17, pp. 487 - 500 (2016)
The molecular hallmarks of epigenetic control. Nature Reviews Genetics
Journal Article
7, 11310 (2016) (2016)
Dynamic and flexible H3K9me3 bridging via HP1beta dimerization establishes a plastic state of condensed chromatin. Nature Communications
Journal Article
164, pp. 353 - 364 (2016)
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell
Journal Article
61, pp. 260 - 273 (2016)
Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program. Molecular Cell 2015
Journal Article
11, pp. 405 - 418 (2015)
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes. Cell Reports 2014
Journal Article
5, 5691 (2014), p. 5691 (2014)
Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. Nature Communications
Journal Article
55, pp. 277 - 290 (2014)
Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells. Molecular Cell 2013
Journal Article
52, pp. 746 - 757 (2013)
Regulation of Heterochromatin Transcription by Snail1/LOXL2 during Epithelial-to-Mesenchymal Transition. Molecular Cell 2012
Journal Article
19, pp. 1023 - 1030 (2012)
A transcription factor-based mechanism for mouse heterochromatin formation. Nature Structural and Molecular Biology
Journal Article
150, pp. 948 - 960 (2012)
Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity. Cell
Journal Article
8, e1002750 (2012)
In vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases. PLoS Genetics 2011
Journal Article
14, pp. 161 - 172 (2011)
Histone Demethylase UTX-1 Regulates C.elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway. Cell Metabolism