Publications of Rolf Kemler

Hoffmeyer, K.; Junghans, D.; Kanzler, B.; Kemler, R.: Trimethylation and Acetylation of ß-Catenin at Lysine 49 Represent Key Elements in ESC Pluripotency. Cell Reports 18, pp. 2815 - 2824 (2017)

del Valle, I.; Rudloff, S.; Carles, A.; Li, Y.; Liszewska, E.; Vogt, R.; Kemler, R.: E-cadherin is required for the proper activation of the Lifr/Gp130 signaling pathway in mouse embryonic stem cells. Development and Stem Cells 140, pp. 1684 - 1692 (2013)

Yukulov, T.; Raggioli, A.; Franz, H.; Kemler, R.: Wnt3a-dependent and -independent Protein Interaction Networks of Chromatin-bound β-catenin in Mouse Embryonic Stem Cells. Molecular and Cellular Proteomics 12, pp. 1980 - 1994 (2013)

Hoffmeyer, K.; Angelo, R.; Rudloff, S.; Anton, R.; Hierholzer, A.; Del Valle, I.; Hein, K.; Vogt, R.; Kemler, R.: Wnt/β-Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells. Science 336, pp. 1549 - 1554 (2012)

Grouls, S.; Iglesias, D. M.; Wentzensen, N.; Moeller, M. J.; Bouchard, M.; Kemler, R.; Goodyer, P.; Niggli, F.; Gröne, H.-J.; Kriz, W. et al.; Koesters, R.: Lineage Specification of Parietal Epithelial Cells Requires β-Catenin/Wnt Signaling. Journal of the American Society of Nephrology 23, pp. 63 - 72 (2012)

Rudloff, S.; Kemler, R.: Differential requirements for β-catenin during mouse development. Development and Stem Cells 139, pp. 3711 - 3721 (2012)

Wray, J.; Kalkan, T.; Gomez-Lopez, S.; Eckardt, D.; Cook, A.; Kemler, R.; Smith, A.: Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nature Cell Biology 13, pp. 838 - 845 (2011)

Kotb, A. M.; Hierholzer, A.; Kemler, R.: Replacement of E-cadherin by N-cadherin in the mammary gland leads to fibrocystic changes and tumor formation. Breast Cancer Research 13, p. R104 - R104 (2011)

Luciani, F.; Champeval, D.; Herbette, A.; Denat, L.; Aylaj, B.; Martinozzi, S.; Ballotti, R.; Kemler, R.; Goding, C. R.; De Vuyst, F. et al.; Larue, L.; Delmas, V.: Biological and mathematical modeling of melanocyte development. Development 138, pp. 3943 - 3954 (2011)

Hierholzer, A.; Kemler, R.: β-Catenin-Mediated Signaling and Cell Adhesion in Postgastrulation Mouse Embryos. Developmental Dynamics 239, pp. 191 - 199 (2010)

Libusova, L.; Stemmler, M. P.; Hierholzer, A.; Schwarz, H.; Kemler, R.: N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development 137, pp. 2297 - 2305 (2010)

Messerschmidt, D. M.; Kemler, R.: Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism. Developmental Biology 344, pp. 129 - 137 (2010)

Hierholzer, A.; Kemler, R.: Cdx1::Cre Allele for Gene Analysis in the Extraembryonic Ectoderm and the Three Germ Layers of Mice at Mid-Gastrulation. Genesis 47, pp. 204 - 209 (2009)

Hierholzer, A.; Kemler, R.: β-Catenin-Mediated Signaling and Cell Adhesion in Postgastrulation Mouse Embryo. Developmental Dynamics 239, pp. 191 - 199 (2009)

Neumeister, B.; Grabosch, A.; Basak, O.; Kemler, R.; Taylor, V.: Neural Progenitors of the Postnatal and Adult Mouse Forebrain Retain the Ability to Self-Replicate, Form Neurospheres, and Undergo Multipotent Differentiation In Vivo. Stem Cells 27, pp. 714 - 723 (2009)

Neumeister, B.; Grabosch, A.; Basak, O.; Kemler, R.; Taylor, V.: Neural progenitors of the Postnatal and Adult Mouse Forebrain Retain the Ability to Self-Replicate, Form Neurospheres, and Undergo Multipotent Differentiation In Vivo. Stem Cells 27, pp. 714 - 723 (2009)

Tulkunova, E.N.; Malashicheva, A.B.; Chikhirzhina, E.V.; Kostyleva, E.I.; Zeng, W.; Luo, J.; Dobrinski, I.; Hierholzer, A.; Kemler, R.; Tomillin, A.N.: E-cadherin as a novel surface marker of spermatogonial stem cells. Tsitologiia 51, pp. 212 - 218 (2009)

Junghans, D.; Heidenreich, M.; Hack, I.; Taylor, V.; Frotscher, M.; Kemler, R.: Postsynaptic and differential localization to neuronal subtypes of protocadherin β16 in the mammalian central nervous system. European Journal of Neuroscience 27, pp. 559 - 571 (2008)

Koch, U.; Wilson, A.; Cobas, M.; Kemler, R.; MacDonald, H. R.; Radtke, F.: Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis. Blood 111, pp. 160 - 164 (2008)

Lin, L.; Cui, L.; Zhou, W.; Dufort, D.; Zhang, X.; Cai, C.-L.; Bu, L.; Yang, L.; Martin, J.; Kemler, R. et al.; Rosenfeld, M.; Chen, J.; Evans, S. M.: β-Catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proceedings of the National Academy of Sciences of the United States of America 104, pp. 9313 - 9318 (2007)

Handa, K.; Takantani-Nakase, T.; Larue, L.; Stemmler, M.; Kemler, R.; Hakomori, S.-i.: Le^x glycan mediates homotypic adhesion of embryonal cells idependently from E-cadherin: A preliminary note. Bochemical and Biophysical Reseach Communications 358, pp. 247 - 252 (2007)

Kan, N. G.; Stemmler, M. P.; Junghans, D.; Kanzler, B.; de Vries, W. N.; Dominis, M.; Kemler, R.: Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm. Development 134, pp. 31 - 41 (2007)

Kreslova, J.; Machon, O.; Ruzickova, J.; Lachova, J.; Wawrousek, E. F.; Kemler, R.; Krauss, S.; Piatigorsky, J.; Kozmik, Z.: Abnormal Lens Morphogenesis and Ectopic Lens Formation in the Absence of β-Cateinin Function. Genesis 45, pp. 157 - 168 (2007)

Jüngling, K.; Eulenberg, V.; Moore, R.; Kemler, R.; Lessmann, V.; Gottmann, K.: N-Cadherin Transsynaptically Regulates Short-Term Plasticity at Glutamatergic Synapses in Embryonic Stem Cell-Derived Neurons. The Journal of Neuroscience 26, pp. 6968 - 6978 (2006)

Olson, L. E.; Tollkuhn, J.; Scafoglio, C.; Krones, A.; Zhang, J.; Ohgi, K. A.; Wu, W.; Taketo, M.; Kemler, R.; Grosschedl, R. et al.; Rose, D.; Li, X.: Homeodomain-Mediated β-Catenin-Dependent Switching Events Dictate Cell-Lineage Determination. Cell 125, pp. 593 - 605 (2006)

Bagheri-Fam, S.; Barrioneuvo, F.; Dohrmann, U.; Günther, T.; Schüle, R.; Kemler, R.; Mallo, M.; Kanzler, B.; Scherer, G.: Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Developmental Biology 291, pp. 382 - 397 (2006)

Haas, I. G.; Frank, M.; Véron, N.; Kemler, R.: Presenilin-dependent Processing and Nuclear Function of γ-Protocadherins. The Journal of Biological Chemistry 280, pp. 9313 - 9319 (2005)

Frank, M.; Ebert, M.; Shan, W.; Phillips, G. R.; Arndt, K.; Colman, D. R.; Kemler, R.: Differential expression of individual gamma-protocadherins during mouse brain development. Molecular and Cellular Neuroscience 29, pp. 603 - 616 (2005)

Junghans, D.; Haas, I. G.; Kemler, R.: Mammalian cadherins and protocadherins: about cell death, synapses and processing. Current Opinion in Cell Biology 17, pp. 1 - 7 (2005)

Junghans, D.; Hack, I.; Frotscher, M.; Taylor, V.; Kemler, R.: β-Cateinin-Mediated Cell-Adhesion Is Vital for Embryonic Forebrain Development. Developmental Dynamics 233, pp. 528 - 539 (2005)