Publications of Tim Lämmermann

Amann, L.; Fell, A.; Monaco, G.; Sankowski, R.; Wu, H. Z. Q.; Jordão, M. J. C.; Borst, K.; Fliegauf, M.; Masuda, T.; Ardura-Fabregat, A. et al.; Paterson, N.; Nent, E.; Cook, J.; Staszewski, O.; Mossad, O.; Falk, T.; Louveau, A.; Smirnov, I.; Kipnis, J.; Lämmermann, T.; Prinz, M.: Extrasinusoidal macrophages are a distinct subset of immunologically active dural macrophages. Science Immunology 9, eadh1129 (2024)

Mihlan, M.; Wissmann, S.; Gavrilov, A.; Kaltenbach, L.; Britz, M.; Franke, K.; Hummel, B.; Imle, A.; Suzuki, R.; Stecher, M. et al.; Glaser, K. M.; Lorentz, A.; Carmeliet, P.; Yokomizo, T.; Hilgendorf, I.; Sawarkar, R.; Diz-Muñoz, A.; Büscher, J. M.; Mittler, G.; Maurer, M.; Krause, K.; Babina, M.; Erpenbeck, L.; Frank, M.; Rambold, A.; Lämmermann, T.: Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay. Cell 187, pp. 5316 - 5335 (2024)

Glaser, K. M.; Egg, M.; Hobitz, S.; Mitterer, M.; Schain-Zota, D.; Schönberger, K.; Schuldes, K.; Cabezas-Wallscheid, N.; Lämmermann, T.; Rambold, A. et al.; Büscher, J. M.: Targeted Metabolomics on Rare Primary Cells. Journal of Visualized Experiments 204, e65690 (2024)

Glaser, K. M.; Doon-Ralls, J.; Walters, N.; Rima, X. Y.; Rambold, A.; Réategui, E.; Lämmermann, T.: Arp2/3 complex and the pentose phosphate pathway regulate late phases of neutrophil swarming. iScience 27, 108656 (2024)

Kaltenbach, L.; Martzloff, P.; Bambach, S. K.; Aizarani, N.; Mihlan, M.; Gavrilov, A.; Glaser, K. M.; Stecher, M.; Thünauer, R.; Thiriot, A. et al.; Heger, K.; Kierdorf, K.; Wienert, S.; von Andrian, U. H.; Schmidt-Supprian, M.; Nerlov, C.; Klauschen, F.; Roers, A.; Bajénoff, M.; Grün, D.; Lämmermann, T.: Slow integrin-dependent migration organizes networks of tissue-resident mast cells. Nature Immunology 24, pp. 915 - 924 (2023)

Zink, A.; Zenke, S.; Wiese, T.; Beyersdorf, N.; Lämmermann, T.; Rohr, J. C.: Analyzing trogocytosis of T lymphocytes by flow cytometry and confocal microscopy. STAR Protocols 4, 102013 (2023)

Schönberger, K.; Mitterer, M.; Glaser, K.; Stecher, M.; Hobitz, S.; Schain-Zota, D.; Schuldes, K.; Lämmermann, T.; Rambold, A.; Cabezas-Wallscheid, N. et al.; Büscher, J. M.: LC-MS-Based Targeted Metabolomics for FACS-Purified Rare Cells. Analytical Chemistry 95, pp. 4325 - 4334 (2023)

Glaser, K. M.; Tarrant, T. K.; Lämmermann, T.: Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions. Frontiers in immunology 13, 1039803 (2022)

Zenke, S.; Sica, M. P.; Steinberg, F.; Braun, J.; Zink, A.; Gavrilov, A.; Hilger, A.; Arra, A.; Brunner-Weinzierl, M.; Elling, R. et al.; Beyersdorf, N.; Lämmermann, T.; Smulski, C. R.; Rohr, J. C.: Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation. Nature Communications 13, 6459 (2022)

Mihlan, M.; Safaiyan, S.; Stecher, M.; Paterson, N.; Lämmermann, T.: Surprises from Intravital Imaging of the Innate Immune Response. Annual Review of Cell and Developmental Biology 38, pp. 18.1 - 18.23 (2022)

Georgantzoglou, A.; Poplimont, H.; Walker, H. A.; Lämmermann, T.; Sarris, M.: A two-step search and run response to gradients shapes leukocyte navigation in vivo. Journal of Cell Biology 221, e202103207 (2022)

Masuda, T.; Amann, L.; Monaco, G.; Sankowski, R.; Staszewski, O.; Krueger, M.; Gaudio, F. D.; He, L.; Paterson, N.; Nent, E. et al.; Fernández-Klett, F.; Yamasaki, A.; Frosch, M.; Fliegauf, M.; Bosch, L. F. P.; Ulupinar, H.; Hagemeyer, N.; Schreiner, D.; Dorrier, C.; Tsuda, M.; Grothe, C.; Joutel, A.; Daneman, R.; Betsholtz, C.; Lendahl, U.; Knobeloch, K.-P.; Lämmermann, T.; Priller, J.; Kierdorf, K.; Prinz, M.: Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 604, pp. 740 - 748 (2022)

Mihlan, M.; Glaser, K. M.; Epple, M. W.; Lämmermann, T.: Neutrophils: Amoeboid Migration and Swarming Dynamics in Tissues. Frontiers in Cell and Developmental Biology 10, 871789 (2022)

Jünger, F.; Ruh, D.; Strobel, D.; Michiels, R.; Huber, D.; Brandel, A.; Madl, J.; Gavrilov, A.; Mihlan, M.; Daller, C. C. et al.; Rog-Zielinska, E. A.; Römer, W.; Lämmermann, T.; Rohrbach, A.: 100 Hz ROCS microscopy correlated with fluorescence reveals cellular dynamics on different spatiotemporal scales. Nature Communications 13, 1758 (2022)

Paterson, N.; Lämmermann, T.: Macrophage network dynamics depend on haptokinesis for optimal local surveillance. eLife 11, e75354, pp. 1 - 32 (2022)

Mossad, O.; Batut, B.; Yilmaz, B.; Dokalis, N.; Mezö, C.; Nent, E.; Nabavi, L. S.; Mayer, M.; Maron, F. J. M.; Büscher, J. M. et al.; de Agüero, M. G.; Szalay, A.; Lämmermann, T.; Macpherson, A. J.; Ganal-Vonarburg, S. C.; Backofen, R.; Erny, D.; Prinz, M.; Blank, T.: Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N⁶-carboxymethyllysine. Nature Neuroscience 25, pp. 295 - 305 (2022)

Mossad, O.; Nent, E.; Woltemate, S.; Folschweiller, S.; Büscher, J. M.; Schnepf, D.; Erny, D.; Staeheli, P.; Bartos, M.; Szalay, A. et al.; Stecher, B.; Vital, M.; Sauer, J. F.; Lämmermann, T.; Prinz, M.; Blank, T.: Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline. Nature aging 1, pp. 1127 - 1136 (2021)

Glaser, K. M.; Mihlan, M.; Lämmermann, T.: Positive feedback amplification in swarming immune cell populations. Current Opinion in Cell Biology 72, pp. 156 - 162 (2021)

Barkaway, A.; Rolas, L.; Joulia, R.; Bodkin, J.; Lenn, T.; Owen-Woods, C.; Reglero-Real, N.; Stein, M.; Vázquez-Martínez, L.; Girbl, T. et al.; Poston, R. N.; Golding, M.; Saleeb, R. S.; Thiriot, A.; von Andrian, U. H.; Duchene, J.; Voisin, M.-B.; Bishop, C. L.; Voehringer, D.; Roers, A.; Rot, A.; Lämmermann, T.; Nourshargh, S.: Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity 54, pp. 1494 - 1510 (2021)

Kienle, K.; Glaser, K. M.; Eickhoff, S.; Mihlan, M.; Knöpper, K.; Reátegui, E.; Epple, M. W.; Gunzer, M.; Baumeister, R.; Tarrant, T. K. et al.; Germain, R. N.; Irimia, D.; Kastenmüller, W.; Lämmermann, T.: Neutrophils self-limit swarming to contain bacterial growth in vivo. Science 372, eabe7729 (2021)

Groß, M.; Speckmann, C.; May, A.; Gajardo-Carrasco, T.; Wustrau, K.; Maier, S. L.; Panning, M.; Huzly, D.; Agaimy, A.; Bryceson, Y. T. et al.; Choo, S.; Chow, C. W.; Dückers, G.; Fasth, A.; Fraitag, S.; Gräwe, K.; Haxelmans, S.; Holzinger, D.; Hudowenz, O.; Hübschen, J.; Khurana, C.; Kienle, K.; Klifa, R.; Korn, K.; Kutzner, H.; Lämmermann, T.; Ledig, S.; Lipsker, D.; Meeths, M.; Naumann-Bartsch, N.; Rascon, J.; Schänzer, A.; Seidl, M.; Tesi, B.; Vauloup-Fellous, C.; Vollmer-Kary, B.; Warnatz, K.; Wehr, C.; Neven, B.; Vargas, P.; Sepulveda, F. E.; Lehmberg, K.; Schmitt-Gräff, A.; Ehl, S.: Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. The journal of allergy and clinical immunology: official publication of the American Academy of Allergy, Asthma and Immunology 149, pp. 388 - 399 (2021)

Arasa, J.; Collado-Diaz, V.; Kritikos, I.; Medina-Sanchez, J. D.; Friess, M. C.; Sigmund, E. C.; Schineis, P.; Hunter, M. C.; Tacconi, C.; Paterson, N. et al.; Nagasawa, T.; Kiefer, F.; Makinen, T.; Detmar, M.; Moser, M.; Lämmermann, T.; Halin, C.: Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Journal of Experimental Medicine 218, p. e20201413 (2021)

Sixt, M.; Lämmermann, T.: T cells: Bridge-and-Channel Commute to the White Pulp. Immunity 52, pp. 721 - 723 (2020)

Zenke, S.; Palm, M. M.; Braun, J.; Gavrilov, A.; Meiser, P.; Böttcher, J. P.; Beyersdorf, N.; Ehl, S.; Gerard, A.; Lämmermann, T. et al.; Schumacher, T. N.; Beltman, J. B.; Rohr, J. C.: Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity 52, pp. 313 - 327 (2020)

Uderhardt, S.; Martins, A. J.; Tsang, J. S.; Lämmermann, T.; Germain, R. N.: Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage. Cell 177, pp. 541 - 555 (2019)

Mauler, M.; Herr, N.; Schoenichen, C.; Witsch, T.; Marchini, T.; Härdtner, C.; Koentges, C.; Kienle, K.; Ollivier, V.; Schell, M. et al.; Dorner, L.; Wippel, C.; Stallmann, D.; Normann, C.; Bugger, H.; Walther, P.; Wolf, D.; Ahrens, I.; Lämmermann, T.; Ho-Tin-Noé, B.; Ley, K.; Bode, C.; Hilgendorf, I.; Duerschmied, D.: Platelet Serotonin Aggravates Myocardial Ischemia/Reperfusion Injury via Neutrophil Degranulation. Circulation 139, pp. 918 - 931 (2019)

Kolter, J.; Feuerstein, R.; Zeis, P.; Hagemeyer, N.; Paterson, N.; d’Errico, P.; Baasch, S.; Amann, L.; Masuda, T.; Lösslein, A. et al.; Gharun, K.; Meyer-Luehmann, M.; Waskow, C.; Franzke, C.-W.; Grün, D.; Lämmermann, T.; Prinz, M.; Henneke, P.: A Subset of Skin Macrophages Contributes to the Seruveillance and Regeneration of Local Nerves. Immunity 50, pp. 1482 - 1497 (2019)

Lämmermann, T.; Kastenmüller, W.: Concepts of GPCR-controlled navigation in the immune system. Immunological Reviews 289, pp. 205 - 231 (2019)

Hülsdünker, J.; Ottmüller, K. J.; Neeff, H. P.; Koyama, M.; Gao, Z.; Thomas, O. S.; Follo, M.; Al-Ahmad, A.; Prinz, G.; Duquesne, S. et al.; Dierbach, H.; Kirschnek, S.; Lämmermann, T.; Blaser, M. J.; Fife, B. T.; Blazar, B. R.; Beilhack, A.; Hill, G. R.; Häcker, G.; Zeiser, R.: Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood 131, pp. 1858 - 1869 (2018)

Andreani, V.; Ramamoorthy, S.; Pandey, A.; Lupar, E.; Nutt, S. L.; Lämmermann, T.; Grosschedl, R.: Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function. Proceedings of the National Academy of Sciences of the United States of America 115, pp. E9630 - E9639 (2018)