Publications of R. Grosschedl

Journal Article (76)

2015
Journal Article
Ramachandran, H.; Herfurth, K.; Grosschedl, R.; Schäfer, T.; Walz, G.: SUMOylation Blocks the Ubiquitin-Mediated Degradatoin of the Nephronophthisis Gene Product Glis2/NPHP7. Plos One 10, e0130275 (2015)
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2014
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Boller, S.; Grosschedl, R.: The regulatory network of B-cell differentiation: a focused view of early B-cell factor 1 function. Immunological Reviews 261, pp. 102 - 115 (2014)
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Rosenbaum, M.; Andreani, V.; Kapoor, T.; Herp, S.; Flach, H.; Duchniewicz, M.; Grosschedl, R.: MZB1 is a GRP94 cochaperone that enables proper immunoglobulin heavy chain biosynthesis upon ER stress. Genes and Development 28, pp. 1165 - 1178 (2014)
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Grosschedl, R.: Establishment and Maintenance of B cell Identity. Cold Spring Harbor Symposia on Quantitative Biology 78, pp. 23 - 30 (2014)
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Okosun, J.; Bödör, C.; Wang, J.; Araf, S.; Yang, C.-Y.; Pan, C.; Boller, S.; Cittaro, D.; Bozek, M.; Iqbal, S. et al.; Matthews, J.; Wrench, D.; Marzec, J.; Tawana, K.; Popov, N.; O'riain, C.; O'Shea, D.; Carlotti, E.; Davies, A.; Lawrie, C. H.; Matolcsy, A.; Calaminici, M.; Norton, A.; Byers, R. J.; Mein, C.; Stupka, E.; Lister, T. A.; Lenz, G.; Montoto, S.; Gribben, J. G.; Fan, Y.; Grosschedl, R.; Chelala, C.; Fitzgibbon, J.: Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nature Genetics 46, pp. 176 - 181 (2014)
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2013
Journal Article
Nechanitzky, R.; Akbas, D.; Scherer, S.; Györy, I.; Hoyler, T.; Ramamoorthy, S.; Diefenbach, A.; Grosschedl, R.: Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nature Immunology 14, pp. 867 - 875 (2013)
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Lokmane, L.; Proville, R.; Narboux-Neme, N.; Györy, I.; Keita, M.; Mailhes, C.; Léna, C.; Gaspar, P.; Grosschedl, R.; Garel, S.: Sensory Map Transfer to the Neocrotex Relies on Pretarget Ordering of Thalamic Axons. Current Biology 23, pp. 810 - 816 (2013)
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Zee, T.; Boller, S.; Györy, I.; Tuckermann, J. P.; Grosschedl, R.; Karsenty, G.: The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Letters 587, pp. 711 - 716 (2013)
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2012
Journal Article
Srinivasan, K.; Leone, D. P.; Bateson, R. K.; Dobreva, G.; Kohwi, Y.; Kohwi-Shigematsu, T.; Grosschedl, R.; McConnell, S. K.: A network of genetic repression and derepression specifies projection fates in the developing neocortex. Proceedings of the National Academy of Sciences of the United States of America 109, pp. 19071 - 19078 (2012)
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Nechanitzky, R.; Dávila, A.; Savarese, F.; Fietze, S.; Grosschedl, R.: Satb1 and Satb2 Are Dispensable for X Chromosome Inactivation in Mice. Developmental Cell 23, pp. 866 - 871 (2012)
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Skokowa, J.; Klimiankou, M.; Klimenkova, O.; Lan, D.; Gupta, K.; Hussein, K.; Carrizosa, E.; Kusnetsova, I.; Li, Z.; Sustmann, C. et al.; Ganser, A.; Zeidler, C.; Kreipe, H.-H.; Burkhardt, J.; Grosschedl, R.; Welte, K.: Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis. Nature Medicine 18, pp. 1550 - 1559 (2012)
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Wei, J.; Shi, Y.; Zheng, L.; Zhou, B.; Inose, H.; Wang, J.; Guo, X. E.; Grosschedl, R.; Karsenty, G.: miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. The Journal of Cell Biology: JCB 197, pp. 509 - 521 (2012)
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Györy, I.; Boller, S.; Nechanitzky, R.; Mandel, E.; Pott, S.; Liu, E.; Grosschedl, R.: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells. Genes and Development 26, pp. 668 - 682 (2012)
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2011
Journal Article
Zhang, J.; Tu, Q.; Grosschedl, R.; Kim, M. S.; Griffin, T.; Drissi, H.; Yang, P.; Chen, J.: Roles of SATB2 in osteogenic differentiation and bone regeneration. Tissue Engineering 17, pp. 1767 - 1776 (2011)
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2010
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Flach, H.; Rosenbaum, M.; Duchniewicz, M.; Kim, S.; Zhang, S. L.; Cahalan, M. D.; Mittler, G.; Grosschedl, R.: Mzb1 Protein Regulates Calcium Homeostasis, Antibody Secretion, and Integrin Activation in Innate-like B Cells. Immunity 33, pp. 723 - 735 (2010)
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Treiber, N.; Treiber, T.; Zocher, G.; Grosschedl, R.: Structure of an Ebf1: DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes and Development 24, pp. 2270 - 2275 (2010)
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Kieslinger, M.; Hiechinger, S.; Dobreva, G.; Consalez, G. G.; Grosschedl, R.: Early B Cell Factor 2 Regulates Hematopoietic Stem Cell Homeostasis in a Cell-Nonautonomous Manner. Cell Stem Cell 7, pp. 496 - 507 (2010)
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Treiber, T.; Mandel, E. M.; Pott, S.; Györy, I.; Firner, S.; Liu, E. T.; Grosschedl, R.: Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression and Transcription - Independent Poising of Chromatin. Immunity 32, pp. 714 - 725 (2010)
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Mandel, E. M.; Grosschedl, R.: Transcription control of early B cell differentiation. Current Opinion in Immunology 22, pp. 161 - 167 (2010)
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Sen, R.; Grosschedl, R.: Memories of lost enhancers. Genes and Development 2, pp. 973 - 979 (2010)
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2009
Journal Article
Savarese, F.; Dávila, A.; Nechanitzky, R.; De la Rosa-Velazquez, I. A.; Pereira, C. F.; Engelke, R.; Takahashi, K.; Jenuwein, T.; Kohwi-Shigematsue, T.; Fisher, A. et al.; Grosschedl, R.: Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes and Development 23, pp. 2625 - 2638 (2009)
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2008
Journal Article
Sustmann, C.; Flach, H.; Ebert, H.; Eastman, Q.; Grosschedl, R.: Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain that Synergizes with β-Catenin. Molecular and Cellular Biology (Washington, DC) 28, pp. 3526 - 3537 (2008)
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Dawlaty, M. M.; Malureanu, L.; Jeganathan, K. B.; Kao, E.; Sustmann, C.; Tahk, S.; Shuai, K.; Grosschedl, R.; van Deursen, J. M.: Resolution of Sister Centromeres Requires RanBP2-Mediated SUMOylation of Topoisomerase IIα. Cell 133, pp. 103 - 115 (2008)
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Nielsen, P.; Grosschedl, R.: Multitasking of Interferon Regulatory Factor-4 in Early B Cells. Immunity 28, pp. 295 - 297 (2008)
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Alcamo, E. A.; Chirivella, L.; Dautzenberg, M.; Dobreva, G.; Farinas, I.; Grosschedl, R.; McConnell, S. K.: Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex. Neuron 57, pp. 364 - 377 (2008)
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Pongubala, J. M. R.; Northrup, D. L.; Lancki, D. W.; Medina, K. L.; Treiber, T.; Bertolino, E.; Thomas, M.; Grosschedl, R.; Allman, D.; Singh, H.: Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nature Immunology 9, pp. 203 - 215 (2008)
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2007
Journal Article
Tolkunova, E.; Malashicheva, A.; Parfenov, V. N.; Sustmann, C.; Grosschedl, R.; Tomilin, A.: PIAS Proteins as Repressors of Oct4 Function. Journal of Molecular Biology (London) 374, pp. 1200 - 1212 (2007)
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Schneider, R.; Grosschedl, R.: Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes and Development 21, pp. 3027 - 3043 (2007)
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Iwatsuki, K.; Liu, H.-X.; Gründer, A.; Singer, M.; Lane, T. F.; Grosschedl, R.; Mistretta, C.; Margolskee, R. F.: Wnt signaling interacts with Shh to regulate taste papilla development. Proceedings of the National Academy of Sciences of the United States of America 104, pp. 2253 - 2258 (2007)
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Roessler, S.; Györy, I.; Imhof, S.; Spivakov, M.; Williams, R. R.; Busslinger, M.; Fischer, A. G.; Grosschedl, R.: Distinct Promoters Mediate the Regulation of Ebf1 Gene Expression by Interleukin-7 and Pax5. Molecular and Cellular Biology (Washington, DC) 27, pp. 579 - 594 (2007)
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