Publications of Marina Freudenberg

Maler, M. D.; Zwick, S.; Kallfass, C.; Engelhard, P.; Shi, H.; Hellig, L.; Zhengyang, P.; Hardt, A.; Zissel, G.; Ruzsics, Z. et al.; Jahnen-Dechent, W.; Martin, S. F.; Nielsen, P. J.; Stolz, D.; Lopatecka, J.; Bastyans, S.; Beutler, B.; Schamel, W. W.; Fejer, G.; Freudenberg, M.: Type I Interferon, Induced by Adenovirus or Adenoviral Vector Infection, Regulates the Cytokine Response to Lipopolysaccharide in a Macrophage Type-Specific Manner. Journal of Innate Immunity 16, pp. 226 - 247 (2024)

Cohen, I.; Rider, P.; Vornov, E.; Tomas, M.; Tudor, C.; Wegner, M.; Brondani, L.; Freudenberg, M.; Mittler, G.; Elisa, F.-M. et al.; Dinarello, C. A.; Apte, R. N.; Schneider, R.: IL-1α is a DNA damage sensor linking genetoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports 5, pp. 1 - 11 (2015)

Fejer, G.; Wegner, M. D.; Györy, I.; Cohen, I.; Engelhard, P.; Voronov, E.; Manke, T.; Ruzsics, Z.; Dölken, L.; Prazeres da Costa, O. et al.; Branzk, N.; Huber, M.; Prasse, A.; Schneider, R.; Apte, R. N.; Galanos, C.; Freudenberg, M. A.: Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions. Proceedings of the National Academy of Sciences Uzs.A. 110, pp. E-2191 - E-2198 (2013)

Yamazaki, T.; Hannani, D.; Poirier-Colame, V.; Ladoire, S.; Locher, C.; Sistigu, A.; Prada, N.; Adjemian, S.; Catani, J. P. P.; Freudenberg, M. et al.; Galanos, C.; André, F.; Kroemer, G.; Zitvogel, L.: Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists. Cell Death and Differentiation 21, pp. 69 - 78 (2013)

Tchaptchet, S.; Gumenscheimer, M.; Kalis, C.; Freudenberg, N.; Hölscher, C.; Kirschning, C. J.; Lamers, M.; Galanos, C.; Freudenberg, M. A.: TLR9-Dependent and Independent Pathways Drive Activation of the Immune System by Propionibacterium Acnes. PLoS ONE 7, p. e39155 - e39155 (2012)

Eigenbrod, T.; Franchi, L.; Munoz-Planillo, R.; Kirschning, C. J.; Freudenberg, M. A.; Núnez, G.; Dalpke, A.: Bacterial RNA Mediates Activation of Caspase-1 and IL-1β Release Independently of TLRs 3, 7, 9 and TRIF but Is Dependent on UNC93B. The Journal of Immunology 189, pp. 328 - 336 (2012)

Esser, P.; Wölfle, U.; Dürr, C.; von Loewenich, F. D.; Schempp, C. M.; Freudenberg, M. A.; Jakob, T.; Martin, S. F.: Contact Sensitzers Induce Skin Inflammation via ROS Production and Hyalurinic Acid Degradation. PLoS ONE 7, p. e41340 - e41340 (2012)

Salomao, R.; Colo Brunialti, M. K.; Rapozo, M. M.; Baggio-Zappia, G. L.; Galanos, C.; Freudenberg, M.: BACTERIAL SENSING, CELL SIGNALING, AND MODULATION OF THE IMMUNE RESPONSE DURING SEPSIS. Shock 38, pp. 227 - 242 (2012)

Deshmukh, S. D.; Kremer, B.; Freudenberg, M.; Bauer, S.; Golenbock, D. T.; Henneke, P.: Macrophages recognize streptococci through bacterial single-stranded RNA. EMBO Reports 12, pp. 71 - 76 (2011)

Fejer, G.; Freudenberg, M.; Greber, U. F.; Gyory, I.: Adenovirus-triggered innate signalling pathways. European Journal of Microbiology and Immunology 4, pp. 279 - 288 (2011)

Keck, S.; Müller, I.; Fejer, G.; Savic, I.; Tchaptchet, S.; Nielsen, P. J.; Galanos, C.; Huber, M.; Freudenberg, M. A.: Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells. The Journal of Immunology 186, pp. 5478 - 5488 (2011)

Martin, S. F.; Esser, P. R.; Weber, F. C.; Jakob, T.; Freudenberg, M. A.; Schmidt, M.; Goebeler, M.: Mechanisms of chemical-induced innate immunity in allergic contact dermatitis. Allergy 66, pp. 1152 - 1163 (2011)

Lauterbach, H.; Bathke, B.; Gilles, S.; Traidl-Hoffmann, C.; Luber, C. A.; Fejer, G.; Freudenberg, M. A.; Davey, G. M.; Vremec, D.; Kallies, A. et al.; Wu, L.; Shortman, K.; Chaplin, P.; Suter, M.; O'Keeffe, M.; Hochrein, H.: Mouse CD8α⁺ DCs and human BDCA3⁺ DCs are major producers of IFN-λ in response to poly IC. Journal of Experimental Medicine 207 (12), pp. 2703 - 2717 (2010)

Heimesaat, M. M.; Nogai, A.; Bereswill, S.; Plickert, R.; Fischer, A.; Loddenkemper, C.; Steinhoff, U.; Tchaptchet, S.; Thiel, E.; Freudenberg, M. A. et al.; Göbel, U. B.; Uharek, L.: MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease. Gut 59, pp. 1079 - 1087 (2010)

Keck, S.; Freudenberg, M.; Huber, M.: Activation of Murine Macrophages via TLR2 and TLR4 is Negatively Regulated by a Lyn/P13K Module and Promoted by SHIP1. The Journal of Immunology 184, pp. 5809 - 5818 (2010)

Schmidt, M.; Raghavan, B.; Müller, V.; Vogl, T.; Fejer, G.; Tchaptchet, S.; Keck, S.; Kalis, C.; Nielsen, P. J.; Galanos, C. et al.; Roth, J.; Skerra, A.; Martin, S.; Freudenberg, M. A.; Goebeler, M.: Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nature Immunology 11, pp. 814 - 819 (2010)

Siegemund, S.; Hartl, A.; von Buttlar, H.; Dautel, F.; Raue, R.; Freudenberg, M. A.; Fejer, G.; Büttner, M.; Köhler, G.; Kirschning, C. J. et al.; Sparwasser, T.; Alber, G.: Conventional Bone Marrow-Derived Dendritic Cells Contribute to Toll-Like Receptor-Independent production of Alpha/Beta Interferon in Response to Inactivate Parapoxvirus Ovis. Journal of Virology 83, pp. 9411 - 9422 (2010)

Tchaptchet, S.; Kirberg, J.; Freudenberg, N.; Schamel, W. W. A.; Galanos, C.; Freudenberg, M. A.: Innate, antigen-independent role for T cells in the activation of the immune system by Propionibacterium acnes. European Journal of Immunology 40, pp. 2506 - 2516 (2010)

Freudenberg, M.; Esser, P. R.; Jakob, T.; Galanos, C.; Martin, S.F.: Innate and adaptive immune responses in contact dermatitis: analogy with infections. Giornale Italiano di Dermatologia e Venereologia 144, pp. 173 - 185 (2009)

Müller-Hübenthal, B.; Azemar, M.; Lorenzen, D.; Huber, M.; Freudenberg, M.; Galanos, C.; Unger, C.; Hildenbrand, B.: Tumour Biology: Tumour-associated Inflammation versus Antitumor Immunity. Anticancer Research 29, pp. 4795 - 4806 (2009)

Zorn, C. N.; Keck, S.; Hendriks, R. W.; Leitges, M.; Freudenberg, M. A.; Huber, M.: Bruton's tyrosine kinase is dispensable for the Toll-like receptor-mediated activation of mast cells. Cellular Signaling 21, pp. 79 - 86 (2009)

Metkar, S. S.; Menaa, C.; Pardo, J.; Wang, B.; Wallich, R.; Freudenberg, M.; Kim, S.; Raja, S.; Shi, L.; Simon, M. M. et al.; Froelich, C. J.: Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response. Immunity 29, pp. 720 - 733 (2008)

Martin, S. F.; Dudda, J. C.; Bachtanian, E.; Lembo, A.; Liller, S.; Dürr, C.; Heimesaat, M.; Bereswill, S.; Fejer, G.; Vassileva, R. et al.; Jakob, T.; Freudenberg, N.; Termeer, C.; Johner, C.; Galanos, C.; Freudenberg, M. A.: Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. Journal of Experimental Medicine 205, pp. 2151 - 2162 (2008)

Cramer, J. P.; Lepenies, B.; Kamena, F.; Hölscher, C.; Freudenberg, M. A.; Burchard, G. D.; Wagner, H.; Kirschning, C. J.; Liu, X.; Seeberger, P. et al.; Jacobs, T.: MyDD/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection. Microbes and Infection 10, pp. 1259 - 1265 (2008)

Fejer, G.; Drechsel, L.; Liese, J.; Schleicher, U.; Ruzsics, Z.; Imelli, N.; Greber, U. F.; Keck, S.; Hildenbrand, B.; Krug, A. et al.; Bogdan, C.; Freudenberg, M. A.: Key role of splenic myeloid DCs in the IFN-αβ response to adenoviruses in vivo. PLoS Pathogens 4, pp. 1 - 21 (2008)

Freudenberg, M. A.; Tchaptchet, S.; Keck, S.; Fejer, G.; Huber, M.; Schütze, N.; Beutler, B.; Galanos, C.: Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity. Immunobiology 213, pp. 193 - 203 (2008)

Hildenbrand, B.; Lorenzen, D.; Sauer, B.; Hertkorn, C.; Freudenberg, M. A.; Peters, J. H.; Nesselhut, T.; Unger, C.: IFN-γ Enhances T_H1 Polarisation of Monocyte-derived Dendritic Cells Matured with Clinical-greade Cytokines Using Serum-free Conditions. Anticancer Research 28, pp. 1467 - 1476 (2008)

Hölscher, C.; Reiling, N.; Schaible, U. E.; Hölscher, A.; Bathmann, C.; Korbel, D.; Lenz, I.; Sonntag, T.; Kröger, S.; Akira, S. et al.; Mossmann, H.; Kirschning, C. J.; Wagner, H.; Freudenberg, M.; Ehlers, S.: Containment of aerogenic Mycobacterium tuberculosis infection in mice does not requrie MyD88 adaptor function for TLR2, -4 and -9. European Journal of Immunology 38, pp. 680 - 694 (2008)

Huai, J.; Firat, E.; Nil, A.; Million, D.; Gaedicke, S.; Kanzler, B.; Freudenberg, M.; van Endert, P.; Kohler, G.; Pahl, H. L. et al.; Aichele, P.; Eichmann, K.; Niedermann, G.: Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice. Proceedings of the National Academy of Sciences of the United States of America 105, pp. 5177 - 5182 (2008)

Kamgang, R. K.; Ramos, I.; Rodrigues Duarte, L.; Ghielmetti, M.; Freudenberg, M.; Dahinden, C.; Padovan, E.: Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists. Medical Microbiology and Immunology 197, pp. 369 - 379 (2008)