Publications of Michael Huber

Kundu, K.; Costa, F.; Huber, M.; Reth, M.; Backofen, R.: Semi-Supervised Prediction of SH2-Peptide Interactions from Imbalanced High-Throughput Data. PLoS ONE 8, p. e62372 - e62372 (2013)

Fejer, G.; Wegner, M. D.; Györy, I.; Cohen, I.; Engelhard, P.; Voronov, E.; Manke, T.; Ruzsics, Z.; Dölken, L.; Prazeres da Costa, O. et al.; Branzk, N.; Huber, M.; Prasse, A.; Schneider, R.; Apte, R. N.; Galanos, C.; Freudenberg, M. A.: Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions. Proceedings of the National Academy of Sciences Uzs.A. 110, pp. E-2191 - E-2198 (2013)

Zorn, C. N.; Pardo, J.; Martin, P.; Kuhny, M.; Simon, M. M.; Huber, M.: Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner. European Journal of Immunology 43, pp. 3209 - 3218 (2013)

Mukherjee, O.; Weingarten, L.; Padberg, I.; Pracht, C.; Sinha, R.; Hochdörfer, T.; Kuppig, S.; Backofen, R.; Reth, M.; Huber, M.: The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: Impact on SHIP1/Ig-α interaction. Biochimica et Biophysica Acta 1823, pp. 206 - 214 (2012)

Keck, S.; Müller, I.; Fejer, G.; Savic, I.; Tchaptchet, S.; Nielsen, P. J.; Galanos, C.; Huber, M.; Freudenberg, M. A.: Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells. The Journal of Immunology 186, pp. 5478 - 5488 (2011)

Mukherjee, O.; Weingarten, L.; Padberg, I.; Pracht, C.; Sinha, R.; Hochdörfer, T.; Kuppig, S.; Backofen, R.; Reth, M.; Huber, M.: The SH2-comain of SHIP1 interacts with the SHIP1 C-terminus: Impact on SHIP1/Ig-α interaction. Biochimica et Biophysica Acta 1823, pp. 206 - 214 (2011)

Keck, S.; Freudenberg, M.; Huber, M.: Activation of Murine Macrophages via TLR2 and TLR4 is Negatively Regulated by a Lyn/P13K Module and Promoted by SHIP1. The Journal of Immunology 184, pp. 5809 - 5818 (2010)

Müller-Hübenthal, B.; Azemar, M.; Lorenzen, D.; Huber, M.; Freudenberg, M.; Galanos, C.; Unger, C.; Hildenbrand, B.: Tumour Biology: Tumour-associated Inflammation versus Antitumor Immunity. Anticancer Research 29, pp. 4795 - 4806 (2009)

Zorn, C. N.; Keck, S.; Hendriks, R. W.; Leitges, M.; Freudenberg, M. A.; Huber, M.: Bruton's tyrosine kinase is dispensable for the Toll-like receptor-mediated activation of mast cells. Cellular Signaling 21, pp. 79 - 86 (2009)

Freudenberg, M. A.; Tchaptchet, S.; Keck, S.; Fejer, G.; Huber, M.; Schütze, N.; Beutler, B.; Galanos, C.: Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity. Immunobiology 213, pp. 193 - 203 (2008)

Minguet, S.; Dopfer, E. P.; Pollmer, C.; Freudenberg, M. A.; Galanos, C.; Reth, M.; Huber, M.; Schamel, W. W.: Enhanced B-cell activation mediated by TLR4 and BCR crosstalk. European Journal of Immunology 38, pp. 2475 - 2487 (2008)

Molendijk, A. J.; Ruperti, B.; Singh, M. K.; Dovzhenko, A.; Ditengou, F. A.; Milia, M.; Westphal, L.; Rosahl, S.; Soellick, T.-R.; Uhrig, J. et al.; Weingarten, L.; Huber, M.; Palme, K.: A cysteine-rich receptor-like kinase NCRK and a pathogen-induced protein kinase RBK1 are Rop GTPase interactors. The Plant Journal 53, pp. 909 - 923 (2008)

Abraham, D.; Oster, H.; Huber, M.; Leitges, M.: The expression pattern of three mast cell specific proteases during mouse development. Molecular Immunology 44, pp. 732 - 740 (2007)

Ali, S.; Huber, M.; Kollewe, C.; Bischoff, S. C.; Falk, W.; Martin, M. U.: IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells. Proceedings of the National Academy of Sciences of the United States of America 104, pp. 18660 - 18665 (2007)

Fehrenbach, K.; Port, F.; Grochowy, G.; Kalis, C.; Bessler, W.; Galanos, C.; Krystal, G.; Freudenberg, M.; Huber, M.: Stimulation of mast cells via FcεR1 and TLR2: The type of ligand determines the outcome. Molecular Immunology 44, pp. 2087 - 2094 (2007)

Gibbs, B. F.; Räthling, A.; Huber, M.; Haas, H.: Substantial differences in the kinetics of histamine release from human basophils caused by varying strengths of IgE-dependent activators. Inflammation Research 56, pp. S1 - S2 (2007)

Grosse, J.; Braun, A.; Varga-Szabo, D.; Beyersdorf, N.; Schneider, B.; Zeitlmann, L.; Hanke, P.; Schropp, P.; Mühlstedt, S.; Zorn, C. et al.; Huber, M.; Schmittwolf, C.; Jagla, W.; Yu, P.; Kerkau, T.; Schulze, H.; Nieswandt, B.: An EF hand mutation in Stim1 causes premature platelet activation and bleeding in mice. The Journal of Clinical Investigation 117, pp. 3540 - 3550 (2007)

Lessmann, E.; Ngo, M.; Leitges, M.; Minguet, S.; Ridgway, N. D.; Huber, M.: Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation. Cellular Signalling 19, pp. 384 - 392 (2007)

Pardo, J.; Wallich, R.; Ebnet, K.; Iden, S.; Zentgraf, H.; Martin, P.; Ekiciler, A.; Prins, A.; Müllbacher, A.; Huber, M. et al.; Simon, M. M.: Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin. Cell Death and Differentiation 14, pp. 1768 - 1779 (2007)

Pracht, C.; Minguet, S.; Leitges, M.; Reth, M.; Huber, M.: Association of protein kinase C-δ with the B cell antigen receptor complex. Cellular Signalling 19, pp. 715 - 722 (2007)

Elis, W.; Lessmann, E.; Oelgeschlager, M.; Huber, M.: Mutations in the inter-SH2 domain of the regulatory subunit of phosphoinositide 3-kinase: effects on catalytic subunit binding and holoenzyme function. Biological Chemistry 387, pp. 1567 - 1573 (2006)

Bläser, S.; Röseler, S.; Rempp, H.; Bartsch, I.; Bauer, H.; Lieber, M.; Lessmann, E.; Weingarten, L.; Busse, A.; Huber, M. et al.; Zieger, B.: Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5. Journal of Pathology 210, pp. 103 - 110 (2006)

Gibbs, B. F.; Räthling, A.; Zillikens, D.; Huber, M.; Haas, H.: Initial FcεRI-mediated signal strength plays a key role in regulating basophil signaling and deactivation. Journal of Allergy and Clinical Immunology 118, pp. 1060 - 1067 (2006)

Huber, M.; Kalis, C.; Keck, S.; Jiang, Z.; Georgel, P.; Du, X.; Shamel, L.; Sovath, S.; Mudd, S.; Beutler, B. et al.; Galanos, C.; Freudenberg, M. A.: R-form LPS, the master key to the activation of TLR4/MD-2-positive cells. European Journal of Immunology 36, pp. 701 - 711 (2006)

Lessmann, E.; Grochowy, G.; Weingarten, L.; Giesemann, T.; Aktories, K.; Leitges, M.; Krystal, G.; Huber, M.: Insulin and insulin-like growth factor-1 promote mast cell survival via activation of the phosphatidylinositol-3-kinase pathway. Experimental Hematology 34, pp. 1532 - 1541 (2006)

Lessmann, E.; Leitges, M.; Huber, M.: A redundant role for PKC-ε in mast cell signaling and effector function. International Immunology 18, pp. 767 - 773 (2006)

Jian, Z.; Georgel, P.; Du, X.; Shamel, L.; Sovath, S.; Mudd, S.; Huber, M.; Kalis, C.; Keck, S.; Galanos, C. et al.; Freudenberg, M.; Beutler, B.: CD14 is required for MyD88-independent LPS signaling. Nature Immunology 6, pp. 565 - 570 (2005)

Gimborn, K.; Lessmann, E.; Kuppig, S.; Krystal, G.; Huber, M.: SHIP Down-Regulates FcεR-1-Induced Degranulation at Supraoptimal IgE or Antigen Levels. The Journal of Immunology 174, pp. 507 - 516 (2005)

Minguet, S.; Huber, M.; Rosenkranz, L.; Schamel, W. W. A.; Reth, M.; Brummer, T.: Adenosine and cAMP are potent inhibitors of the NF-κB pathway downstream of immunoreceptors. European Journal of Immunology 35, pp. 31 - 41 (2005)

Brummer, T.; Elis, W.; Reth, M.; Huber, M.: B-Cell Signal Transduction. Methods in Molecular Biology 271, pp. 189 - 212 (2004)