Publications of Julian Pardo

Zorn, C. N.; Pardo, J.; Martin, P.; Kuhny, M.; Simon, M. M.; Huber, M.: Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B dependent manner. European Journal of Immunology 43, pp. 3209 - 3218 (2013)

Ivanova, S.; Gregorc, U.; Vidergar, N.; Javier, R.; Bredt, D. S.; Vandenabeele, P.; Pardo, J.; Simon, M. M.; Turk, V.; Banks, L. et al.; Turk, B.: MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis. Cell Death and Disease 2, p. e116 - e116 (2011)

Joeckel, L. T.; Wallich, R.; Martin, P.; Sanchez-Martinez, D.; Weber, F. C.; Martin, S. F.; Borner, C.; Pardo, J.; Froelich, C.; Simon, M. M.: Mouse granzyme K has pro-inflammatory potential. Cell Death and Differentiation 18, pp. 1112 - 1119 (2011)

Aguiló, J. I.; Anel, A.; Catalán, E.; Sebastián, A.; Acín-Pérez, R.; Naval, J.; Wallich, R.; Simon, M. M.; Pardo, J.: Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation. Immunology and Cell Biology 88, pp. 545 - 554 (2010)

Anel, A.; Bleakley, C.; Borner, C.; Golstein, P.; Krammer, P. H.; Müllbacher, A.; Pardo, J.; Simon, M. M.; Trapani, J.A.: EMBO workshop on cytotoxicity, cell death and the immune system. Cell Death and Differentiation 16, pp. 790 - 793 (2009)

Froehlich, C. J.; Pardo, J.; Simon, M. M.: Granule-associated serine proteases: granzymes might not just be killer proteases. Cell 30, pp. 117 - 123 (2009)

Herz, J.; Pardo, J.; Kashkar, H.; Schramm, M.; Kuzmenkina, E.; Bos, E.; Wiegmann, K.; Wallich, R.; Peters, P. J.; Herzig, S. et al.; Schmelzer, E.; Krönke, M.; Simon, M. M.; Utermöhlen, O.: Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes. Nature Immunology 10, pp. 761 - 768 (2009)

Metkar, S. S.; Menaa, C.; Pardo, J.; Wang, B.; Wallich, R.; Freudenberg, M.; Kim, S.; Raja, S.; Shi, L.; Simon, M. M. et al.; Froelich, C. J.: Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response. Immunity 29, pp. 720 - 733 (2008)

Pardo, J.; Wallich, R.; Martin, P.; Urban, C.; Rongvaux, A.; Flavell, R. A.; Müllbacher, A.; Borner, C.; Simon, M. M.: Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs. Cell Death and Differentiation 15, pp. 567 - 579 (2008)

Pardo, J.; Wallich, R.; Ebnet, K.; Iden, S.; Zentgraf, H.; Martin, P.; Ekiciler, A.; Prins, A.; Müllbacher, A.; Huber, M. et al.; Simon, M. M.: Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin. Cell Death and Differentiation 14, pp. 1768 - 1779 (2007)

Sugui, J. A.; Pardo, J.; Chang, Y. C.; Müllbacher, A.; Zarember, K. A.; Galvez, E. M.; Brinster, L.; Zerfas, P.; Gallin, J. I.; Simon, M. M. et al.; Kwon-Chung, K. J.: Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus. Eukaryotic Cell 6, pp. 1552 - 1561 (2007)

Sugui, J. A.; Pardo, J.; Chang, Y. C.; Zarember, K. A.; Nardone, G.; Galvez, E. M.; Müllbacher, A.; Gallin, J. I.; Simon, M. M.; Kwon-Chung, K. J.: Gliotoxin is a virulence factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone. Eukaryotic Cell 6, pp. 1562 - 1569 (2007)

Pardo, J.; Urban, C.; Galvez, E. M.; Ekert, P. G.; Müller, U.; Kwon-Chung, J.; Lobigs, M.; Müllbacher, A.; Wallich, R.; Borner, C. et al.; Simon, M. M.: The motchondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice. The Journal of Cell Biology 174, pp. 509 - 519 (2006)

Martin, P.; Wallich, R.; Pardo, J.; Müllbacher, A.; Munder, M.; Modolell, M.; Simon, M. M.: Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes? Blood 106, pp. 2871 - 2878 (2005)