Publications

Benkisser-Petersen, M.; Buchner, M.; Dörffel, A.; Dühren-von-Minden, M.; Claus, R.; Kläsener, K.; Leberecht, K.; Burger, M.; Dierks, C.; Jumaa, H. et al.; Malavasi, F.; Reth, M.; Veelken, H.; Duyster, J.; Zirlik, K.: Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia. PLoS One 11, p. e0169159 (2016)

Rauch, K. S.; Hils, M.; Lupar, E.; Minguet, S.; Sigvardsson, M.; Rottenberg, M. E.; Izcue, A.; Schachtrup, C.; Schachtrup, K.: Id3 Maintains Foxp3 Expression in Regulatory T Cells by Controlling a Transcriptional Network of E47, Spi-B, and SOCS3. Cell Reports 17, pp. 2827 - 2836 (2016)

Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, pp. 2310 - 2324 (2016)

Aranda-Orgilles, B.; Saldaña-Meyer, R.; Wang, E.; Trompouki, E.; Fassl, A.; Lau, S.; Mullenders, J.; Rocha, P. P.; Raviram, R.; Guillamot, M. et al.; Sánchez-Díaz, M.; Wang, K.; Kayembe, C.; Zhang, N.; Amoasii, L.; Choudhuri, A.; Skok, J. A.; Schober, M.; Reinberg, D.; Sicinski, P.; Schrewe, H.; Tsirigos, A.; Zon, L. I.; Aifantis, I.: MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell 19, pp. 784 - 799 (2016)

Brenker, K.; Osthof, K.; Yang, J.; Reth , M.: LED Thermo Flow - Combining Optogenetics with Flow Cytometry. Journal of visualized experiments 118, p. e54707 - e54707 (2016)

Iwanami, N.; Sikora, K.; Richter, A. S.; Mönnich, M.; Guerri, L.; Soza-Ried, C.; Lawir, D.-F.; Mateos, F.; Hess, I.; O’Meara, C. P. et al.; Schorpp, M.; Boehm, T.: Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports 17, pp. 2259 - 2270 (2016)

Herrtwich, L.; Nanda, I.; Evangelou, K.; Nikolova, T.; Horn, V.; Sagar, S.; Erny, D.; Stefanowski, J.; Rogell, L.; Klein, C. et al.; Gharun, K.; Follo, M.; Seidl, M.; Kremer, B.; Münke, N.; Senges, J.; Fliegauf, M.; Aschman, T.; Pfeifer, D.; Sarrazin, S.; Sieweke, M. H.; Wagner, D.; Dierks, C.; Haaf, T.; Ness, T.; Zaiss, M. M.; Voll, R. E.; Deshmukh, S. D.; Prinz, M.; Goldmann, T.; Hölscher, C.; Hauser, A. E.; Lopez-Contreras, A. J.; Grün, D.; Gorgoulis, V.; Diefenbach, A.; Henneke, P.; Triantafyllopoulou, A.: DNA Damage Signaling Instructs Polypoid Macrophage Fate in Granulomas. Cell 167, pp. 1264 - 1280 (2016)

Stunnenberg, H. G.; Hirst, M.; Consortium, T. I. H. E.; Pospisilik, J. A.: The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell, pp. 1145 - 1149 (2016)

Durek, P.; Nordström, K.; Gasparoni, G.; Salhab, A.; Kressler, C.; de Almeida, M.; Bassler, K.; Ulas, T.; Schmidt, F.; Xiong, J. et al.; Glažar, P.; Klironomos, F.; Sinha, A.; Kinkley, S.; Yang, X.; Arrigoni, L.; Amirabad, A. D.; Ardakani, F. B.; Feuerbach, L.; Gorka, O.; Ebert, P.; Müller, F.; Li, N.; Frischbutter, S.; Schlickeiser, S.; Cendon, C.; Fröhler, S.; Felder, B.; Gasparoni, N.; Imbusch, C. D.; Hutter, B.; Zipprich, G.; Tauchmann, Y.; Reinke, S.; Wassilew, G.; Hoffmann, U.; Richter, A. S.; Sieverling, L.; Consortium, D.; Chang, H.-D.; Syrbe, U.; Kalus, U.; Eils, J.; Brors, B.; Manke, T.; Ruland, J.; Lengauer, T.; Rajewsky, N.; Chen, W.; Dong, J.; Sawitzki, B.; Chung, H.-R.; Rosenstiel, P.; Schulz, M. H.; Schultze, J. L.; Radbruch, A.; Walter, J.; Hamann, A.; Polansky, J. K.: Epigenomic Profiling of Human CD4⁺ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development. Immunity 45, pp. 1148 - 1161 (2016)

Greenberg, M. V. C.; Glaser, J.; Borsos, M.; Marjou, F. E.; Walter, M.; Teissandier, A.; Bourc'his, D.: Transient transcription in the early embryo sets an epigenetic state that programs postnatal growth. Nature Genetics 49, pp. 110 - 118 (2016)

Clapes, T.; Lefkopoulos, S.; Trompouki, E.: Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance. Frontiers in immunology 7, p. e487 - e487 (2016)

Schnappauf, O.; Beyes, S.; Dertmann, A.; Freihen, V.; Frey, P.; Rose, K.; Michoel, T.; Grosschedl, R.; Hecht, A.: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing. Biochimica et Biophysica Acta (BBA) 1859, pp. 1353 - 1367 (2016)

Cameron , A. M.; Lawless, S. J.; Pearce, E. J.: Metabolism and acetylation in innnate immune cell function and fate. Seminars in Immunology 28, pp. 408 - 416 (2016)

Muraro, M. J.; Dharmadhikari, G.; Grün, D.; Groen, N.; Dielen, T.; Jansen, E.; van Gurp, L.; Engelse, M. A.; Carlotti, F.; de Koning, E. J.P. et al.; van Oudenaarden, A.: A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Systems 3, pp. 385 - 394 (2016)

Chatterjee, A.; Seyfferth, J.; Lucci, J.; Glisbach, R.; Preissl, S.; Böttinger, L.; Martensson, C. U.; Panhale, A.; Stehle, T.; Kretz, O. et al.; Sahyoun, A. H.; Avilov, S.; Eimer, S.; Hein, L.; Pfanner, N.; Becker, T.; Akhtar, A.: MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria. Cell 167, pp. 722 - 738 (2016)

Duteil, D.; Tosic, M.; Lausecker, F.; Nenseth, H. Z.; Müller, J. M.; Urban, S.; Willmann, D.; Petroll, K.; Messaddeq, N.; Arrigoni, L. et al.; Manke, T.; Kornfeld, J.-W.; Brüning, J. C.; Zagoriy, V.; Meret, M.; Dengjel, J.; Kanouni, T.; Schüle, R.: Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue. Cell Reports 17, pp. 1008 - 1021 (2016)

Huang, S. C.-C.; Smith, A. M.; Everts, B.; Colonna, M.; Pearce, E. L.; Schilling, J. D.; Pearce, E. J.: Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis is Essential for Macrophage Alternative Activation. Immunity 45, pp. 817 - 830 (2016)

Koidl, S.; Eisenhardt, N.; Fatouros, C.; Droescher, M.; Chaugule, V. K.; Pichler, A.: The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability. The International Journal of Biochemistry & Cell Biology 79, pp. 478 - 487 (2016)

Volkmann, C.; Brings, N.; Becker, M.; Hobeika, E.; Yang, J.; Reth, M.: Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens. The EMBO Journal 35, pp. 2371 - 2381 (2016)

Hilde, K. L.; Levine, A. J.; Hinckley, C. A.; Montgomery, J. M.; Gullo, M.; Driscoll, S. P.; Grosschedl, R.; Kohwi, Y.; Kohwi-Shigematsu, T.; Pfaff, S.: Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron 91, pp. 763 - 776 (2016)

Boukhaled, G. M.; Cordeiro, B.; Deblois, G.; Dimitrov, V.; Bailey, S. D.; Holowka, T.; Domi, A.; Guak, H.; Chiu, H.-H. C.; Everts, B. et al.; Pearce, E. J.; Lupien, M.; White, J. H.; Krawczyk, C. M.: The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence. Cell 16, pp. 1829 - 1837 (2016)

O'Sullivan, D.; Kelly, B.; Pearce, E. L.: When Hexokinase Gets that NAG-ing Feeling. Cell Metabolism 24, pp. 198 - 200 (2016)

Grün, D.; Muraro, M. J.; Boisset, J.-C.; Wiebrands, K.; Lyubimova, A.; Dharmadhikari, G.; van den Born, M.; Jansen, E.; Clevers, H.; de Koning, E. J.P. et al.; van Oudenaarden, A.: De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell 19, pp. 266 - 277 (2016)

Allis, C. D.; Jenuwein, T.: The molecular hallmarks of epigenetic control. Nature Reviews Genetics 17, pp. 487 - 500 (2016)

Lam, W. Y.; Becker, A. M.; Kennerly, K. M.; Wong, R.; Curtis, J. D.; Llufrio, E. M.; McCommis, K. S.; Fahrmann, J.; Pizzato, H. A.; Nunley, R. M. et al.; Lee, J.; Wolfgang, M. J.; Patti, G. J.; Finck, B. N.; Pearce, E. L.; Bhattacharya, D.: Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells. Immunity 45, pp. 60 - 73 (2016)

Ramirez, F.; Ryan, D. P.; Grüning, B.; Bhardwaj, V.; Kilpert, F.; Richter, A. S.; Heyne, S.; Dündar, F.; Mnake, T.: deepTools2: a next generation web server for deep-sequencing data analysis. Nucleic Acids Research (London) 44, pp. W160 - W165 (2016)

Buck, M. D.; O’Sullivan, D.; Geltink, R. I. K.; Curtis, J. D.; Chang, C.-H.; Sanin, D. E.; Qiu, J.; Kretz, O.; Braas, D.; van der Windt, G. J.W. et al.; Chen, Q.; Huang, S. C.-C.; O’Neill, C. M.; Edelson, B. T.; Pearce, E. J.; Sesaki, H.; Huber, T. B.; Rambold, A.; Pearce, E. L.: Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming. Cell 166, pp. 63 - 76 (2016)

Wu, D.; Sanin, D. E.; Everts, B.; Chen, Q.; Qiu, J.; Buck, M. D.; Patterson, A.; Smith, A. M.; Chang, C.-H.; Liu, Z. et al.; Artyomov, M. N.; Pearce, E. J.; Cella, M.; Pearce, E. J.: Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. Immunity 44, pp. 1325 - 1326 (2016)

Kaiko, G. E.; Ryu, S. H.; Koues, O. I.; Collins, P. L.; Solnica-Krezel, L.; Pearce, E. J.; Pearce, E. L.; Oltz, E. M.; Stappenbeck, T. S.: The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Cell 167, pp. 1708 - 1720 (2016)

Kong, L.; Tang, J.; Little, J. P.; Yu, Y.; Lämmermann, T.; Lin, C. P.; Germain, R. N.; Cui, M.: Continuous volumetric imaging via an optical phase-locked ultrasound lens. Nature methods 12, pp. 759 - 762 (2016)