Luca Scorrano - Keeping mitochondria in shape: a matter of life and death
Max Planck Special Guest Lecture Series
- Short-term change: The seminar will start at 14:30.
- Datum: 15.03.2018
- Uhrzeit: 14:30 c.t. - 15:30
- Vortragende(r): Luca Scorrano
- Venetian Institute of Molecular Medicine (VIMM), Padova, Italy
- Ort: MPI-IE
- Raum: Main Lecture Hall
- Gastgeber: Post-Doc representatives
CV
Scorrano obtained his M.D. and Ph.D. degrees from the University of Padua Medical School in 1996 and 2001. In 2000, he moved to Boston were he worked as a Post-Doc at Harvard Medical School. After stations as Assistant Scientist at the Dulbecco-Telethon Institute, VIMM (2003-2007) and as a Full Professor in the Department of Cell Physiology and Metabolism at University of Geneva Medical School (2007-2013) he was appointed a Full Professor of Biochemistry at University of Padua in 2013 and since 2014 he serves as Scientific Director of the Venetian Institute of Molecular Medicine.
Research
His laboratory is investigating the molecular mechanisms that control mitochondrial shape and how changes in mitochondrial morphology influence mitochondrial and cellular physiology. He discovered the process of mitochondrial cristae remodeling that allows complete cytochrome c release during apoptosis. Since 2004, his lab discovered a “molecular staple” holding cristae junctions tight and exploited it in vivo to correct mitochondrial diseases and blunt tissue damage; the first molecular bridge between ER and mitochondria; how mitochondrial shape controls the outcome of autophagy; the link between cristae shape and mitochondrial respiration; the essential role of mitochondrial fusion in heart development.
source: University of Padua