Karim-Jean Armache - Catalytic and non-catalytic mechanisms of chromatin modifiers

The Armache lab wants to understand the organization and dynamics of chromatin complexes important for the regulation of gene expression, both at the genetic and epigenetic levels. The team uses a combination of structural approaches, including x-ray crystallography and electron microscopy, coupled with biophysical and biochemical experimentation to study mechanisms by which gene silencing complexes impact chromatin structure and repress transcription. (source)

Follow Karim-Jean on twitter: @kjarmache

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