MPS: Stefanie Grosswendt - Cell communication uncovered in single-cell resolved neighborhoods
Max Planck Seminar
- Datum: 23.04.2025
- Uhrzeit: 13:30 - 14:30
- Vortragende: Stefanie Grosswendt
- Berlin Institute of Health @Charité, Germany
- Ort: MPI-IE
- Raum: Lecture Hall
- Gastgeber: Nicola Iovino
Dr. Stefanie Grosswendt, head of a BIH junior research group in the joint research focus “Single Cell Approaches for Personalized Medicine” of the Berlin Institute of Health (BIH), the MDC and Charité, Berlin, joins our lecture series to present a talk on “Cell communication uncovered in single-cell resolved neighborhoods”.
The Grosswendt Lab investigates how cell-cell interactions shape gene expression and function in both normal development and disease. Using single-cell and spatial transcriptomics, the lab studies how diverse cell states influence each other within their tissue context, with a focus on the neural crest lineage. A key goal is to understand how tumors, such as neuroblastoma and melanoma, hijack developmental programs to drive abnormal growth. By integrating experimental and computational approaches, the lab aims to uncover mechanisms of cellular communication, improve tumor detection, and develop more effective treatments.