Publikationen von Gerhard Mittler

Lee, C.; Quintana, A.; Suppanz, I.; Gomez-Auli, A.; Mittler, G.; Cissé, I. I.: Light-induced targeting enables proteomics on endogenous condensates. Cell 187, S. 7079 - 7090 (2024)

Wogram, E.; Sümpelmann, F.; Dong, W.; Rawat, E.; Maestre, I. F.; Fu, D.; Braswell, B.; Khalil, A.; Büscher, J. M.; Mittler, G. et al.; Borner, G. H. H.; Vlachos, A.; Tholen, S.; Schilling, O.; Bell, G. W.; Rambold, A.; Akhtar, A.; Schnell, O.; Beck, J.; Abu-Reh, M.; Prinz, M.; Jaenisch, R.: Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity 57, S. 2216 - 2231 (2024)

Chen, H.-R.; Sun, Y.; Mittler, G.; Rumpf, T.; Shvedunova, M.; Grosschedl, R.; Akhtar, A.: MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation. Cell Reports 43, 114682 (2024)

Mihlan, M.; Wissmann, S.; Gavrilov, A.; Kaltenbach, L.; Britz, M.; Franke, K.; Hummel, B.; Imle, A.; Suzuki, R.; Stecher, M. et al.; Glaser, K. M.; Lorentz, A.; Carmeliet, P.; Yokomizo, T.; Hilgendorf, I.; Sawarkar, R.; Diz-Muñoz, A.; Büscher, J. M.; Mittler, G.; Maurer, M.; Krause, K.; Babina, M.; Erpenbeck, L.; Frank, M.; Rambold, A.; Lämmermann, T.: Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay. Cell 187, S. 5316 - 5335 (2024)

Phongbunchoo, Y.; Braikia, F.-Z.; Pessoa-Rodrigues, C.; Ramamoorthy, S.; Ramachandran, H.; Grosschedl, A.; Ma, F.; Cauchy, P.; Akhtar, A.; Sen, R. et al.; Mittler, G.; Grosschedl, R.: YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment. Cell Reports 43, 114456 (2024)

Atinbayeva, N.; Valent, I.; Zenk, F.; Loeser, E.; Rauer, M.; Herur, S.; Quarato, P.; Pyrowolakis, G.; Gomez-Auli, A.; Mittler, G. et al.; Cecere, G.; Erhardt, S.; Tiana, G.; Zhan, Y.; Iovino, N.: Inheritance of H3K9 methylation regulates genome architecture in Drosophila early embryos. The EMBO Journal (2024)

Zhou, Y.; Panhale, A.; Shvedunova, M.; Balan, M.; Gomez-Auli, A.; Holz, H.; Seyfferth, J.; Helmstädter, M.; Kayser, S.; Zhao, Y. et al.; Erdogdu, N. U.; Grzadzielewska, I.; Mittler, G.; Manke, T.; Akhtar, A.: RNA damage compartmentalization by DHX9 stress granules. Cell 187, S. 1701 - 1718 (2024)

Baixauli, F.; Piletic, K.; Puleston, D. J.; Villa, M.; Field, C. S.; Flachsmann, L. J.; Quintana, A.; Rana, N.; Edwards-Hicks, J.; Matsushita, M. et al.; Stanczak, M. A.; Grzes, K. M.; Kabat, A. M.; Fabri, M.; Caputa, G.; Kelly, B.; Corrado, M.; Musa, Y.; Duda, K. J.; Mittler, G.; O'Sullivan, D.; Sesaki, H.; Jenuwein, T.; Büscher, J. M.; Pearce, E. J.; Sanin, D. E.; Pearce, E. L.: An LKB1-mitochondria axis controls T_H17 effector function. Nature 610, S. 555 - 561 (2022)

Bayer, M.; Boller, S.; Ramamoothy, S.; Zolotarev, N.; Cauchy, P.; Iwanami, N.; Mittler, G.; Boehm, T.; Grosschedl, R.: Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 36, S. 901 - 915 (2022)

Puleston, D. J.; Baixauli, F.; Sanin, D. E.; Edwards-Hicks, J.; Villa, M.; Kabat, A. M.; Kamiński, M. M.; Stanckzak, M.; Weiss, H. J.; Grzes, K. M. et al.; Piletic, K.; Field, C. S.; Corrado, M.; Haessler, F.; Wang, C.; Musa, Y.; Schimmelpfennig, L.; Flachsmann, L.; Mittler, G.; Yosef, N.; Kuchroo, V. K.; Büscher, J. M.; Balabanov, S.; Pearce, E. J.; Green, D. R.; Pearce, E. L.: Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell 184, S. 4186 - 4202 (2021)

Montavon, T.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Ryan, D.; Musa, Y.; Mittler, G.; Meyer, A. G.; Genoud, C. et al.; Jenuwein, T.: Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Nature Communications 12, 4359 (2021)

Duda, K. J.; Ching, R. W.; Jerabek, L.; Shukeir, N.; Erikson, G.; Engist, B.; Onishi-Seebacher, M.; Perrera, V.; Richter, F.; Mittler, G. et al.; Fritz, K.; Helm, M.; Knuckles, P.; Bühler, M.; Jenuwein, T.: m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin. Nucleic Acids Research (London) 49, S. 5568 - 5587 (2021)

Akerman, I.; Maestro, M. A.; Franco, E. D.; Grau, V.; Flanagan, S.; García-Hurtado, J.; Mittler, G.; Ravassard, P.; Piemonti, L.; Ellard, S. et al.; Hattersley, A. T.; Ferrer, J.: Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports 35, 108981 (2021)

Stanczak, M. A.; Sanin, P. D. E.; Apostolova, P.; Nerz, G.; Lampaki, D.; Hofmann, M.; Steinmann, D.; Krohn-Grimberghe, M.; Thimme, R.; Mittler, G. et al.; Waller, C. F.; Pearce, E. J.; Pearce, E. L.: IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals. Nature Communications 12, 2133 (2021)

Kelly, B.; Carrizo, G. E.; Edwards-Hicks, J.; Sanin, P. D. E.; Stanczak, M. A.; Priesnitz, C.; Flachsmann, L. J.; Jonathan, D. C.; Mittler, G.; Musa, Y. et al.; Becker, T.; Büscher, J. M.; Pearce, E. L.: Sulfur sequestration promotes multicellularity during nutrient limitation. Nature 591, S. 471 - 476 (2021)

Wang, Y.; Zolotarev, N.; Yang, C.-Y.; Rambold, A.; Mittler, G.; Grosschedl, R.: A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin. Immunity 53, S. 1151 - 1167 (2020)

Carrasco, J.; Rauer, M.; Hummel, B.; Grzejda, D.; Alfonso-Gonzalez, C.; Lee, Y.; Wang, Q.; Puchalska, M.; Mittler, G.; Hilgers, V.: ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue. Molecular Cell 80, S. 156 - 163 (2020)

Karoutas, A.; Szymanski, W. G.; Rausch, T.; Guhathakurta, S.; Rog-Zielinska, E. A.; Peyronnet, R.; Seyfferth, J.; Chen, H.-R.; de Leeuw, R.; Herquel, B. et al.; Kimura, H.; Mittler, G.; Kohl, P.; Medalia, O.; Korbel, J. O.; Akhtar, A.: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nature Cell Biology 21, S. 1248 - 1260 (2019)

Puleston, D. J.; Buck, M. D.; Geltink, R. I. K.; Kyle, R. L.; Caputa, G.; O’Sullivan, D.; Cameron, A. M.; Castoldi, A.; Musa, Y.; Kabat, A. M. et al.; Zhang, Y.; Flachsmann, L. J.; Field, C. S.; Patterson, A. E.; Scherer, S.; Alfei, F.; Baixauli, F.; Austin, S. K.; Kelly, B.; Matsushita, M.; Curtis, J. D.; Grzes, K. M.; Villa, M.; Corrado, M.; Sanin, D. E.; Qiu, J.; Pällman, N.; Paz, K.; Maccari, M. E.; Blazar, B. R.; Mittler, G.; Büscher, J.; Zehn, D.; Rospert, S.; Pearce, E. J.; Balabanov, S.; Pearce, E. L.: Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation. Cell Metabolism 30, S. 352 - 363 (2019)

Panhale, A.; Richter , F. M.; Ramírez, F.; Shvedunova, M.; Manke, T.; Mittler, G.; Akhtar, A.: CAPRI enables comparison of evolutionary conserved RNA interacting regions. Nature Communications 10, 2682 (2019) (2019)

Sanin, D. E.; Matsushita, M.; Klein-Geltink, R.; Grzes, K.; van Bakker, N. T.; Corrado, M.; Kabat, A.; Buck, M. D.; Qiu, J.; Lawless, S. J. et al.; Cameron, A.; Villa, M.; Baixauli Celda, F.; Patterson, A. E.; Hässler, F.; Curtis, J. D.; O’Neill, C. M.; O'Sullivan, D.; Wu, D.; Mittler, G.; Huang, S. C.-C.; Pearce, E. L.; Pearce, E. J.: Mitochondrial Membrane Potential Regulates Nuclear Gene Expression Macrophages Exposed to Prostaglandin. Immunity 49, S. 1021 - 1033 (2018)

Ramos Pittol, J. M.; Oruba, A.; Mittler, G.; Saccani , S.; van Essen, D.: Zbrv7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors. PLoS Biology 16, S. e2004526 (2018)

Giaimo, B. D.; Ferrante, F.; Vallejo, D. M.; Hein, K.; Gutierrez-Perez, I.; Nist, A.; Stiewe, T.; Mittler, G.; Herold, S.; Zimmermann, T. et al.; Bartkuhn, M.; Schwarz, P.; Oswald, F.; Dominguez, M.; Borggrefe, T.: Histone variant H2A.Z deposition and acetlyation directs the canonical Notch signaling response. Nucleic Acids Research (London) 46, S. 8197 - 8215 (2018)

Musa, Y. R.; Boller, S.; Puchalska, M.; Grosschedl, R.; Mittler, G.: Comprehensive Proteomic Investigation of Ebf1 Heterozygosity in Pro-B Lymphocytes Ulilizing Data Independent Acquisition. Journal of Proteome Research 17, S. 76 - 85 (2018)

Aktas, T.; Ilik, I. A.; Maticzka, D.; Bhardwaj, V.; Rodrigues , C. P.; Mittler, G.; Manke, T.; Backofen, R.; Akhtar, A.: DHX9 Suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature 544, S. 115 - 119 (2017)

Yang, C.-Y.; Ramamoorthy, S.; Boller, S.; Rosenbaum, M.; Gil, A. R.; Mittler, G.; Imai, Y.; Kuba, K.; Grosschedl, R.: Interaction of CCR4-NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis. Genes and Development 30, S. 2310 - 2324 (2016)

Chlamydas, S.; Holz, H.; Samata, M.; Chelmicki, T.; Georgiev, P.; Pelechano, V.; Dündar, F.; Dasmeh, P.; Mittler, G.; Tavares Cadete, F. et al.; Ramirez, F.; Conrad, T.; Wei, W.; Raja, S.; Manke, T.; Luscombe, N. M.; Steinmetz, L. M.; Akhtar, A.: Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Nature Structural and Molecular Biology 23, S. 580 - 589 (2016)

Trung, N. T.; Kremer, E.; Mittler, G.: Biochemical and cellular characterization of transcription factors binding to the hyperconserved core promoter-associated M4 motif. BMC Genomics 17, S. 693 (2016)

Cohen, I.; Rider, P.; Vornov, E.; Tomas, M.; Tudor, C.; Wegner, M.; Brondani, L.; Freudenberg, M.; Mittler, G.; Elisa, F.-M. et al.; Dinarello, C. A.; Apte, R. N.; Schneider, R.: IL-1α is a DNA damage sensor linking genetoxic stress signaling to sterile inflammation and innate immunity. Scientific Reports 5, S. 1 - 11 (2015)

Prasad, S.; Gaedicke, S.; Machein, M.; Mittler, G.; Braun , F.; Hettich, M.; Firat, E.; Klingner, K.; Schüler, J.; Wider, D. et al.; Wäsch, R. M.; Herold-Mende, C.; Elsässer-Beile, U.; Niedermann, G.: Effective Eradication of Gliioblastoma Stem Cells by Local Application of AC133/CD133-Specific T-cell Engaging Antibody and CD8 T Cells. Cancer research: an official organ of the American Association for Cancer Research 75, S. 2166 - 2176 (2015)