Iovino Lab

Publikationen von E. Hobeika

Zeitschriftenartikel (35)

2015
Zeitschriftenartikel
Fiala, G. J.; Janowska, I.; Prutek, F.; Hobeika, E.; Satapathy, A.; Sprenger, A.; Plum, T.; Seidl, M.; Dengjel, J.; Reth, M. et al.; Cesca, F.; Brummer, T.; Minguet, S.; Schamel, W. W. A.: Kidins220/ARMS binds to the B cell antigen recptor and regulates B cell development and activation. The Journal of Experimental Medicine 212 (10), S. 1693 - 1708 (2015)
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Zeitschriftenartikel
Yamamoto, K.; Lee, B.J.; Li, C.; Dubois, R.L.; Hobeika, E.; Bhagat, G.; Zha, S.: Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice. Leukemia 29, S. 1414 - 1424 (2015)
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DOI
Zeitschriftenartikel
Hobeika, E.; Zerdoun Levit, E.; Anastasopoulou, V.; Pohlmeyer, R.; Altmeier, S.; Alsedeq, A.; Dobenecker, M.-W.; Pelanda, R.; Reth, M.: CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. The EMBO Journal 34, S. 925 - 939 (2015)
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Zeitschriftenartikel
Hobeika, E.; Nielsen, P. J.; Medgysi, D.: Signaling mechanisms regulating B-lymphocyte activation and tolerance. Journal of Molecular Medicine 93, S. 143 - 158 (2015)
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Zeitschriftenartikel
Königsberger, S.; Weis, V.; Prodöhl, J.; Stehling, M.; Hobeika, E.; Reth, M.; Kiefer, F.: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germina center counterselection mechanisms. European Journal of Immunology 45, S. 603 - 611 (2015)
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DOI
2014
Zeitschriftenartikel
Baracho, G. V.; Cato, M. H.; Zhu, Z.; Jaren, O. R.; Hobeika, E.; Reth, M.; Rickert, R. C.: PDK1 regulates B cell differentiation and homeostasis. Proceedings of the National Academy of Sciences, USA, S. 9573 - 9578 (2014)
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Zeitschriftenartikel
Alsadeq, A.; Hobeika, E.; Medgyesi, D.; Kläsener, K.; Reth, M.: The Role of the Syk/Shp-1 Kinase-Phosphatase Equilibrium in B Cell Development and Signaling. The Journal of Immunology 193, S. 268 - 276 (2014)
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Zeitschriftenartikel
Grötsch, B.; Brachs, S.; Lang, C.; Luther, J.; Derer, A.; Schlötzer-Schrehardt, U.; Bozec, A.; Fillatreau, S.; Berberich, I.; Hobeika, E. et al.; Reth, M.; Wagner, E. F.; Schett, G.; Mielenz, D.; David, J.-P.: The AP-1 transcription factor Fra1 ihhibits follicular B cell differentiation into plasma cells. The Journal of Experimental Medicine 211, S. 2199 - 2212 (2014)
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Zeitschriftenartikel
Hug, E.; Hobeika, E.; Reth, M.; Jumaa, H.: Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation. Oncogene 33, S. 3730 - 3741 (2014)
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Zeitschriftenartikel
Klasen, C.; Ohl, K.; Sternkopf, M.; Shachar, I.; Schmitz, C.; Heussen, N.; Hobeika, E.; Levit-Zerdoun, E.; Tenbrock, K.; Reth, M. et al.; Bernhagen, J.; El Bounkari, O.: MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling. The Journal of Immunology 192, S. 5273 - 5284 (2014)
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Zeitschriftenartikel
Kläsener, K.; Maity, P. C.; Hobeika, E.; Yang, J.; Reth, M.: B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. eLife 3, S. 1 - 17 (2014)
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Zeitschriftenartikel
Königsberger, S.; Weis, V.; Prodöhl, J.; Stehling, M.; Hobeika, E.; Reth, M.; Kiefer, F.: Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. European Journal of Immunology 45, S. 603 - 611 (2014)
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Zeitschriftenartikel
Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phsphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. Journal of Experimental Medicine 211, S. 427 - 440 (2014)
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Zeitschriftenartikel
Medgyesi, D.; Hobeika, E.; Biesen, R.; Kollert, F.; Taddeo, A.; Voll, R. E.; Hiepe, F.; Reth, M.: The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling an controls B cell autoimmunity. The Journal of Experimental Medicine 211, S. 427 - 440 (2014)
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Zeitschriftenartikel
Umiker, B. R.; McDonald, G.; Larbi, A.; Medina, C. O.; Hobeika, E.; Reth, M.; Imanishi-Kari, T.: Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE. European Journal of Immunology 44, S. 3093 - 3108 (2014)
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2013
Zeitschriftenartikel
Zietra, N.; Lyszkiewicz, M.; Puchalka, J.; Pei, G.; Gutierrez, M. G.; Lienenklaus, S.; Hobeika, E.; Reth, M.; Martins dos Santos, V. A. P.; Krueger, A. et al.; Weiss, S.: Immunoglobulins drive terminal maturation of splenic dendritic cells. Proceedings of the National Academy of Sciences Uzs.A. 110, S. 2282 - 2287 (2013)
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2012
Zeitschriftenartikel
Hao, Z.; Duncan, G. S.; Su, Y.-W.; Li, W. Y.; Silvester, J.; Hong, C.; You, H.; Brenner, D.; Gorrini, C.; Haigth, J. et al.; Wakeham, A.; You-Ten, A.; McCracken, S.; Elia, A.; Li, Q.; Detmar, J.; Juriscova, A.; Hobeika, E.; Reth, M.; Sheng, Y.; Lang, P. A.; Ohashi, P. S.; Zhong, Q.; Wang, X.; Mak, T. W.: The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of Experimental Medicine 209, S. 173 - 186 (2012)
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Zeitschriftenartikel
Hoving, J. C.; Kirstein, F.; Nieuwenhuizen, N. E.; Fick, L. C. E.; Hobeika, E.; Reth, M.; Brombacher, F.: B Cells That Produce Immunoglobulin E Mediate Colitis in BALB/c Mice. Gastroenterology 142, S. 96 - 108 (2012)
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2011
Zeitschriftenartikel
Kiss, E. A.; Vonarbourg, C.; Kopfmann, S.; Hobeika, E.; Finke, D.; Esser, C.; Diefenbach, A.: Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lympoid Follicles. Science 334, S. 1561 - 1565 (2011)
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Zeitschriftenartikel
Winkelmann, R.; Sandrock, L.; Porstner, M.; Roth, E.; Mathews, M.; Hobeika, E.; Reth, M.; Kahn, M. L.; Schuh, W.; Jäck, H.-M.: B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2. Proceedings of the National Academy of Sciences U.S.A. 108, S. 710 - 715 (2011)
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Zeitschriftenartikel
Rowh, M. A. W.; DeMicco, A.; Horowitz, J. E.; Yin, B.; Yang-Iott, K. S.; Fusello, A. M.; Hobeika, E.; Reth, M.; Bassing, C. H.: Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations. Oncogene 30, S. 4757 - 4764 (2011)
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Zeitschriftenartikel
Ziegler, C.; Goldmann, O.; Hobeika, E.; Geffers, R.; Peters, G.; Medina, E.: The dynamics of T cells during persistent Staphylococcus aureus infection: from antigen-reactivity to in vivo anergy. EMBO Molecular Medicine 3, S. 652 - 666 (2011)
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2010
Zeitschriftenartikel
Werner, M.; Hobeika, E.; Hassan, J.: Role of PI3K in the generation and survival of B cells. Immunological Reviews 237, S. 55 - 71 (2010)
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2009
Zeitschriftenartikel
Babbe, H.; McMenamin, J.; Hobeika, E.; Wang, J.; Rodig, S. J.; Reth, M.; Leder, P.: Genomic Instability Resulting from Blm Deficiency Compromises Development, Maintenance, and Function of the B Cell Lineage. The Journal of Immunology 182, S. 347 - 360 (2009)
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Zeitschriftenartikel
Düber, S.; Hafner, M.; Krey, M.; Lienenklaus, S.; Roy, B.; Hobeika, E.; Reth, M.; Buch, T.; Waisman, A.; Kretschmer, K. et al.; Weiss, S.: Induction of B cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood 114, S. 4960 - 4967 (2009)
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2008
Zeitschriftenartikel
Köhler, F.; Hug, E.; Catrin, E.; Meixlsperger, S.; Hobeika, E.; Kofer, J.; Wardemann, H.; Jumaa, H.: Autoreactive B Cell Receptors Mimic Autonomous Pre-B Cell Receptor Signaling and Induce Proliferation of Early B Cells. Immunity 29, S. 912 - 921 (2008)
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Zeitschriftenartikel
Kulathu, Y.; Hobeika, E.; Turchinovich, G.; Reth, M.: The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development. The EMBO Journal 27, S. 1333 - 1344 (2008)
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Zeitschriftenartikel
Thomas, L. R.; Miyashita, H.; Cobb, R. M.; Pierce, S.; Tachibana, M.; Hobeika, E.; Reth, M.; Shinkai, Y.; Oltz, E. M.: Functional Analysis of Histone Methyltransferase G9a in B and T Lymphocytes. The Journal of Immunology 181, S. 485 - 493 (2008)
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2007
Zeitschriftenartikel
Liu, H.; Schmidt-Supprian, M.; Shi, Y.; Hobeika, E.; Barteneva, N.; Jumaa, H.; Pelanda, R.; Reth, M.; Skok, J.; Rajewsky, K. et al.; Shi, Y.: Yin Yang 1 is a critical regulator of B-cell development. Genes & Development 21, S. 1179 - 1189 (2007)
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2006
Zeitschriftenartikel
Hobeika, E.; Thiemann, S.; Storch, B.; Jumaa, H.; Nielsen, P. J.; Pelanda, R.; Reth, M.: Testing gene function early in the B cell lineage in mb1-cre mice. Proceedings of the National Academy of Sciences of the USA, S. 13789 - 13794 (2006)
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