Publikationen von Sebastian Herzog

Alkhatib, A.; Werner, M.; Hug, E.; Herzog, S.; Eschbach, C.; Faraidun, H.; Köhler, F.; Wossning, T.; Jumaa, H.: FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination. The Journal of Experimental Medicine 209, S. 395 - 406 (2012)

Herzog, S.; Jumaa, H.: Self-recognition and clonal selection: autoreactivity drives the generation of B cells. Current Opinion in Immunology 24, S. 166 - 172 (2012)

Hurtz, C.; Hatzi, K.; Cerchietti, L.; Braig, M.; Park, E.; Kim, Y.-m.; Herzog, S.; Ramezani-Rad, P.; Jumaa, H.; Müller, M. C. et al.; Hofmann, W.-K.; Hochhaus, A.; Ye, B. H.; Agarwal, A.; Druker, B. J.; Shah, N. P.; Melnick, A. M.; Müschen, M.: BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. The Journal of Experimental Medicine 208, S. 2163 - 2174 (2011)

Duy, C.; Hurtz, C.; Shojaee, S.; Cerchietti, L.; Geng, H.; Swaminathan, S.; Klemm, L.; Kweon, S.-m.; Nahar, R.; Braig, M. et al.; Park, E.; Kim, Y.-m.; Hofmann, W.-K.; Herzog, S.; Jumaa, H.; Koeffler, H. P.; Yu, J. J.; Heisterkamp, N.; Graeber, T. G.; Wu, H.; Ye, B. H.; Melnick, A.; Müschen, M.: BCL6 enables Ph⁺ actue lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 473, S. 384 - 388 (2011)

Duy, C.; Yu, J. J.; Nahar, R.; Swaminathan, S.; Kweon, S.-M.; Polo, J. M.; Valls, E.; Klemm, L.; Shojaee, S.; Cerchietti, L. et al.; Schuh, W.; Jäck, H.-M.; Hurtz, C.; Ramezani-Rad, P.; Herzog, S.; Jumaa, H.; Koeffler, H. P.; Moreno de Alberán, I.; Melnick, A. M.; Ye, B. H.; Müschen, M.: BCL6 is critical for the development of a diverse primary B cell repertoire. The Journal of Experimental Medicine 207, S. 1209 - 1221 (2010)

Herzog, S.; Reth, M.; Jumaa, H.: Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nature Reviews Immunology 9, S. 195 - 205 (2009)

Trageser, D.; Iacobucci, I.; Nahar, R.; Duy, C.; von Levetzow, G.; Klemm, L.; Park, E.; Schuh, W.; Gruber, T.; Herzog, S. et al.; Kim, Y.-m.; Hofmann, W.-K.; Li, A.; Storlazzi, C. T.; Jäck, H.-M.; Groffen, J.; Martinelli, G.; Heisterkamp, N.; Jumaa, H.; Müschen, M.: Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome- positive acute lymphoblastic leukemia requries IKAROS function. The Journal of Experimental Medicine 206, S. 1739 - 1753 (2009)

Herzog, S.; Hug, E.; Meixlsperger, S.; Paik, J.-H.; dePinho, R. A.; Reth, M.; Jumaa, H.: SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. Nature Immunology 9, S. 623 - 631 (2008)

Herzog, S.; Jumaa, H.: The N Terminus of the Non-T Cell Activation Linker (NTAL) Confers Inhbitory Effects on Pre-B Cell Differentiation. The Journal of Immunology 178, S. 2336 - 2343 (2007)

Wossning, T.; Herzog, S.; Köhler, F.; Meixlsperger, S.; Kulathu, Y.; Mittler, G.; Abe, A.; Fuchs, U.; Borkhardt, A.; Hassan, J.: Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells. Journal of Experimental Medicine 203, S. 2829 - 2840 (2006)

Brummer, T.; Martin, P.; Herzog, S.; Misawa, Y.; Daly, R. J.; Reth, M.: Functional analysis of the regulatory requirements of B-Raf and B-Raf^V600E oncoprotein. Oncogene 25, S. 6262 - 6276 (2006)

Klein, F.; Feldhahn, N.; Herzog, S.; Sprangers, M.; Mooster, J. L.; Jumaa, H.; Müschen, M.: BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells. Oncogene 25, S. 1118 - 1124 (2006)

Sprangers, M.; Feldhahn, N.; Herzog, S.; Hansmann, M.-L.; Reppel, M.; Hescheler, J.; Jumaa, H.; Siebert, R.; Müschen, M.: The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells. Oncogene 25, S. 5056 - 5062 (2006)

Feldhahn, N.; Klein, F.; Mooster, J. L.; Hadweh, P.; Sprangers, M.; Wartenberg, M.; Bekhite, M. M.; Hofmann, W.-K.; Herzog, S.; Jumaa, H. et al.; Rowley, J. D.; Müschen, M.: Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells. The Journal of Experimental Medicine 201, S. 1837 - 1852 (2005)

Köhler, F.; Storch, B.; Kulathu, Y.; Herzog, S.; Kuppig, S.; Reth, M.; Jumaa, H.: A leucine zipper in the N terminus confers membrane association to SLP-65. Nature Immunology 6, S. 204 - 210 (2005)

Su, Y.-w.; Herzog, S.; Lotz, M.; Feldhahn, N.; Müschen, M.; Jumaa, H.: The molecular requirements for LAT-mediated differentiation and the role of LAT in limiting pre-B cell expansion. European Journal of Immunology 34, S. 3614 - 3622 (2004)

Herzog, S.: Comparative genetic immunization of BALB/C and SLP-65-/- mice and BAFF binding to B cell subsets. Albert-Ludwigs-Universität, Freiburg im Breisgau (2003)

Herzog, S.: The role of antigen receptor signaling in normal B cell development, tumorigenesis and autoimmunity. Dissertation, Albert-Ludwigs-University, Freiburg (2008)