Iovino Lab

Publikationen von H. Jumaa

Zeitschriftenartikel (49)

2015
Zeitschriftenartikel
Maity, P. C.; Blount, A.; Jumaa, H.; Ronneberger, O.; Lillemeier, B. F.; Reth, M.: B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science Signaling 8, S. ra93 (2015)
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DOI
2014
Zeitschriftenartikel
Hug, E.; Hobeika, E.; Reth, M.; Jumaa, H.: Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation. Oncogene 33, S. 3730 - 3741 (2014)
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2013
Zeitschriftenartikel
Yaktapour, N.; Übelhart, R.; Schüler, J.; Aumann, K.; Dierks, C.; Burger, M.; Pfeifer, D.; Jumaa, H.; Veelken, H.; Brummer, T. et al.; Zirlik, K.: Insulin-like grwoth factor-1 receptor (IGFIR) as a novel target in chronic lymphocytic leukemia. Blood 122, S. 1621 - 1633 (2013)
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Zeitschriftenartikel
Ramezani-Rad, P.; Geng, H.; Hurtz, C.; Chan, L. N.; Chen, Z.; Jumaa, H.; Melnick, A.; Paletta, E.; Carroll, W. L.; Lefebvre, V. et al.; Müschen, M.: SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia. Blood 121, S. 148 - 155 (2013)
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Zeitschriftenartikel
Sen, S.; Jumaa, H.; Webster, N. J. G.: Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function. Nature Communications 4, S. 1336 - 1347 (2013)
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Zeitschriftenartikel
Sen, S.; Jumaa, H.; Webster, N. J. G.: Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function. Nature Communications 4 (4) (2013)
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DOI
2012
Zeitschriftenartikel
Decker, S.; Zirlik, K.; Djebatchie, L.; Hartmann, D.; Ihorst, G.; Schmitt-Graeff, A.; Herchenbach, D.; Jumaa, H.; Warmuth, M.; Veelken, H. et al.; Dierks, C.: Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL. Blood 119, S. 997 - 1007 (2012)
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Zeitschriftenartikel
Alkhatib, A.; Werner, M.; Hug, E.; Herzog, S.; Eschbach, C.; Faraidun, H.; Köhler, F.; Wossning, T.; Jumaa, H.: FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination. The Journal of Experimental Medicine 209, S. 395 - 406 (2012)
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Zeitschriftenartikel
Dühren-von Minden, M.; Übelhart, R.; Schneider, D.; Wossning, T.; Bach, M. P.; Buchner, M.; Hofmann, D.; Surova, E.; Follo, M.; Köhler, F. et al.; Wardemann, H.; Zirlik, K.; Veelken, H.; Jumaa, H.: Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling. Nature 489, S. 309 - 312 (2012)
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Zeitschriftenartikel
Herzog, S.; Jumaa, H.: Self-recognition and clonal selection: autoreactivity drives the generation of B cells. Current Opinion in Immunology 24, S. 166 - 172 (2012)
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2011
Zeitschriftenartikel
Nahar, R.; Ramezani-Rad, P.; Mossner, M.; Duy, C.; Cherchietti, L.; Geng, H.; Dovat, S.; Jumaa, H.; Ye, B. H.; Melnick, A. et al.; Müschen, M.: Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC. Blood 118, S. 4174 - 4178 (2011)
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Zeitschriftenartikel
Hurtz, C.; Hatzi, K.; Cerchietti, L.; Braig, M.; Park, E.; Kim, Y.-m.; Herzog, S.; Ramezani-Rad, P.; Jumaa, H.; Müller, M. C. et al.; Hofmann, W.-K.; Hochhaus, A.; Ye, B. H.; Agarwal, A.; Druker, B. J.; Shah, N. P.; Melnick, A. M.; Müschen, M.: BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. The Journal of Experimental Medicine 208, S. 2163 - 2174 (2011)
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Zeitschriftenartikel
Duy, C.; Hurtz, C.; Shojaee, S.; Cerchietti, L.; Geng, H.; Swaminathan, S.; Klemm, L.; Kweon, S.-m.; Nahar, R.; Braig, M. et al.; Park, E.; Kim, Y.-m.; Hofmann, W.-K.; Herzog, S.; Jumaa, H.; Koeffler, H. P.; Yu, J. J.; Heisterkamp, N.; Graeber, T. G.; Wu, H.; Ye, B. H.; Melnick, A.; Müschen, M.: BCL6 enables Ph+ actue lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 473, S. 384 - 388 (2011)
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Zeitschriftenartikel
Eschbach, C.; Bach, M. P.; Fidler, I.; Pelanda, R.; Köhler, F.; Rajewsky, K.; Jumaa, H.: Efficient generation of B lymphocytes by recognition of self-antigens. European Journal of Immunology, S. 2397 - 2403 (2011)
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2010
Zeitschriftenartikel
Buchner, M.; Baer, C.; Prinz, G.; Dierks, C.; Burger, M.; Zenz, T.; Stilgenbauer, S.; Jumaa, H.; Veelken, H.; Zirlik, K.: Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia. Blood 115, S. 4497 - 4506 (2010)
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Zeitschriftenartikel
Duy, C.; Yu, J. J.; Nahar, R.; Swaminathan, S.; Kweon, S.-M.; Polo, J. M.; Valls, E.; Klemm, L.; Shojaee, S.; Cerchietti, L. et al.; Schuh, W.; Jäck, H.-M.; Hurtz, C.; Ramezani-Rad, P.; Herzog, S.; Jumaa, H.; Koeffler, H. P.; Moreno de Alberán, I.; Melnick, A. M.; Ye, B. H.; Müschen, M.: BCL6 is critical for the development of a diverse primary B cell repertoire. The Journal of Experimental Medicine 207, S. 1209 - 1221 (2010)
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Zeitschriftenartikel
Übelhart, R.; Bach, M. P.; Eschbach, C.; Wossning, T.; Reth, M.; Jumaa, H.: N-linked glycosylation selectively regulates autonomous precursor BCR function. Nature Immunology 11, S. 759 - 765 (2010)
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2009
Zeitschriftenartikel
Klemm, L.; Duy, C.; Iacobucci, I.; Kuchen, S.; von Levetzow, G.; Feldhahn, N.; Henke, N.; Li, Z.; Hoffmann, T. K.; Kim, Y.-m. et al.; Hofmann, W.-K.; Jumaa, H.; Groffen, J.; Heisterkamp, N.; Martinelli, G.; Lieber, M. R.; Casellas, R.; Müschen, M.: The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug Resistance in Chronic Myeloid Leukemia. Cancer Cell 16, S. 232 - 245 (2009)
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Zeitschriftenartikel
Herzog, S.; Reth, M.; Jumaa, H.: Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nature Reviews Immunology 9, S. 195 - 205 (2009)
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Zeitschriftenartikel
Huck, K.; Feyen, O.; Niehues, T.; Rüschendorf, F.; Hübner, N.; Laws, H.-J.; Telieps, T.; Knapp, S.; Wacker, H.-H.; Meindl, A. et al.; Jumaa, H.; Borkhardt, A.: Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation. The Journal of Clincal Investigation 119, S. 1350 - 1358 (2009)
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Zeitschriftenartikel
Trageser, D.; Iacobucci, I.; Nahar, R.; Duy, C.; von Levetzow, G.; Klemm, L.; Park, E.; Schuh, W.; Gruber, T.; Herzog, S. et al.; Kim, Y.-m.; Hofmann, W.-K.; Li, A.; Storlazzi, C. T.; Jäck, H.-M.; Groffen, J.; Martinelli, G.; Heisterkamp, N.; Jumaa, H.; Müschen, M.: Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome- positive acute lymphoblastic leukemia requries IKAROS function. The Journal of Experimental Medicine 206, S. 1739 - 1753 (2009)
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2008
Zeitschriftenartikel
Köhler, F.; Hug, E.; Catrin, E.; Meixlsperger, S.; Hobeika, E.; Kofer, J.; Wardemann, H.; Jumaa, H.: Autoreactive B Cell Receptors Mimic Autonomous Pre-B Cell Receptor Signaling and Induce Proliferation of Early B Cells. Immunity 29, S. 912 - 921 (2008)
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Zeitschriftenartikel
Herzog, S.; Hug, E.; Meixlsperger, S.; Paik, J.-H.; dePinho, R. A.; Reth, M.; Jumaa, H.: SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. Nature Immunology 9, S. 623 - 631 (2008)
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2007
Zeitschriftenartikel
Meixlsperger, S.; Köhler, F.; Wossning, T.; Reppel, M.; Müschen, M.; Jumaa, H.: Conventional Light Chains Inhibit the Autonomous Signaling Capacity of the B Cell Receptor. Immunity 26, S. 323 - 333 (2007)
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Zeitschriftenartikel
Feldhahn, N.; Henke, N.; Melchoir, K.; Duy, C.; Ndikung Soh, B.; Klein, F.; von Levetzow, G.; Giebel, B.; Li, A.; Hofmann, W.-K. et al.; Jumaa, H.; Müschen, M.: Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells. The Journal of Experimental Medicine 204, S. 1157 - 1166 (2007)
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Zeitschriftenartikel
Herzog, S.; Jumaa, H.: The N Terminus of the Non-T Cell Activation Linker (NTAL) Confers Inhbitory Effects on Pre-B Cell Differentiation. The Journal of Immunology 178, S. 2336 - 2343 (2007)
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Zeitschriftenartikel
Liu, H.; Schmidt-Supprian, M.; Shi, Y.; Hobeika, E.; Barteneva, N.; Jumaa, H.; Pelanda, R.; Reth, M.; Skok, J.; Rajewsky, K. et al.; Shi, Y.: Yin Yang 1 is a critical regulator of B-cell development. Genes & Development 21, S. 1179 - 1189 (2007)
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Zeitschriftenartikel
Storch, B.; Meixlsperger, S.; Jumaa, H.: The Ig-α ITAM is required for efficient differentiation but not proliferation of pre-B cells. Euroepan Journal of Immunology 37, S. 252 - 260 (2007)
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Zeitschriftenartikel
Thompson, E. C.; Cobb, B. S.; Sabbattini, P.; Meixelsperger, S.; Parelho, V.; Liberg, D.; Taylor, B.; Dillon, N.; Georgopoulos, K.; Jumaa, H. et al.; Smale, S. T.; Fisher, A. G.; Merkenschlager, M.: Ikaros DNA-Binding Proteins as Integral Components of B Cell Developmental-Stage-Specific Regulatory Circuits. Immunity 26, S. 335 - 344 (2007)
MPG.PuRe
2006
Zeitschriftenartikel
Hobeika, E.; Thiemann, S.; Storch, B.; Jumaa, H.; Nielsen, P. J.; Pelanda, R.; Reth, M.: Testing gene function early in the B cell lineage in mb1-cre mice. Proceedings of the National Academy of Sciences of the USA, S. 13789 - 13794 (2006)
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