Max-Planck-Institut für Immunbiologie und Epigenetik

Publikationen von Asifa Akhtar

Alle Typen

Zeitschriftenartikel (69)

2024

Zeitschriftenartikel

Wogram, E.; Sümpelmann, F.; Dong, W.; Rawat, E.; Maestre, I. F.; Fu, D.; Braswell, B.; Khalil, A.; Büscher, J. M.; Mittler, G. et al.; Borner, G. H. H.; Vlachos, A.; Tholen, S.; Schilling, O.; Bell, G. W.; Rambold, A.; Akhtar, A.; Schnell, O.; Beck, J.; Abu-Reh, M.; Prinz, M.; Jaenisch, R.: Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity 57, S. 2216 - 2231 (2024)

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Zeitschriftenartikel

Chen, H.-R.; Sun, Y.; Mittler, G.; Rumpf, T.; Shvedunova, M.; Grosschedl, R.; Akhtar, A.: MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation. Cell Reports 43, 114682 (2024)

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publisher-version

Zeitschriftenartikel

Phongbunchoo, Y.; Braikia, F.-Z.; Pessoa-Rodrigues, C.; Ramamoorthy, S.; Ramachandran, H.; Grosschedl, A.; Ma, F.; Cauchy, P.; Akhtar, A.; Sen, R. et al.; Mittler, G.; Grosschedl, R.: YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment. Cell Reports 43, 114456 (2024)

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publisher-version

Zeitschriftenartikel

Kulkarni, T.; Akhtar, A.: Nuclei facing the tissue surface get fuel for development. Nature 630, S. 312 - 314 (2024)

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Zeitschriftenartikel

Zhou, Y.; Panhale, A.; Shvedunova, M.; Balan, M.; Gomez-Auli, A.; Holz, H.; Seyfferth, J.; Helmstädter, M.; Kayser, S.; Zhao, Y. et al.; Erdogdu, N. U.; Grzadzielewska, I.; Mittler, G.; Manke, T.; Akhtar, A.: RNA damage compartmentalization by DHX9 stress granules. Cell 187, S. 1701 - 1718 (2024)

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publisher-version

2023

Zeitschriftenartikel

Sun, Y.; Wiese, M.; Hmadi, R.; Karayol, R.; Seyfferth, J.; Greene, J. A. M.; Erdogdu, N. U.; Deboutte, W.; Arrigoni, L.; Holz, H. et al.; Renschler, G.; Hirsch, N.; Foertsch, A.; Basilicata, M. F.; Stehle, T.; Shvedunova, M.; Bella, C.; Rodrigues, C. P.; Schwalb, B.; Cramer, P.; Manke, T.; Akhtar, A.: MSL2 ensures biallelic gene expression in mammals. Nature 624, S. 173 - 181 (2023)

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publisher-version

Zeitschriftenartikel

Guhathakurta, S.; Erdogdu, N. U.; Hoffmann, J. J.; Grzadzielewska, I.; Schendzielorz, A.; Seyfferth, J.; Mårtensson, C. U.; Corrado, M.; Karoutas, A.; Warscheid, B. et al.; Pfanner, N.; Becker, T.; Akhtar, A.: COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function. Nature Metabolism 5, S. 1931 - 1952 (2023)

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publisher-version

Zeitschriftenartikel

Tsang, T. H.; Wiese, M.; Helmstädter, M.; Stehle, T.; Seyfferth, J.; Shvedunova, M.; Holz, H.; Walz, G.; Akhtar, A.: Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Science Advances 9, eadh5598 (2023)

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publisher-version

Zeitschriftenartikel

Iyer, S. S.; Sun, Y.; Seyfferth, J.; Manjunath, V.; Samata, M.; Alexiadis, A.; Kulkarni, T.; Gutierrez, N.; Georgiev, P.; Shvedunova, M. et al.; Akhtar, A.: The NSL complex is required for piRNA production from telomeric clusters. Life science alliance 6, e202302194 (2023)

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publisher-version

Zeitschriftenartikel

Akhtar, A.: Asifa Akhtar. Current Biology 33, S. R286 - R287 (2023)

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2022

Zeitschriftenartikel

Shvedunova, M.; Akhtar, A.: Modulation of cellular processes by histone and non-histone protein acetylation. Nature Reviews Molecular Cell Biology 23, S. 329 - 349 (2022)

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2021

Zeitschriftenartikel

Pessoa Rodrigues, C.; Chatterjee, A.; Wiese, M.; Stehle, T.; Szymanski, W. G.; Shvedunova, M.; Akhtar, A.: Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice. Nature Communications 12, 6212 (2021)

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publisher-version

Zeitschriftenartikel

Pessoa Rodrigues, C.; Akhtar, A.: Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells. Science Advances 7 (32), eabi5987 (2021)

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publisher-version

Zeitschriftenartikel

Keller Valsecchi, C. I.; Marois, E.; Basilicata, M. F.; Georgiev, P.; Akhtar, A.: Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila. Life science alliance 4, e202000996 (2021)

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publisher-version

Zeitschriftenartikel

Clapes, T.; Polyzou, A.; Prater, P.; Sagar; Morales-Hernández, A.; Ferrarini, M. G.; Kehrer, N.; Lefkopoulos, S.; Bergo, V.; Hummel, B. et al.; Obier, N.; Maticzka, D.; Bridgeman, A.; Herman, J. S.; Ilik, I.; Klaeylé, L.; Rehwinkel, J.; McKinney-Freeman, S.; Backofen, R.; Akhtar, A.; Cabezas-Wallscheid, N.; Sawarkar, R.; Rebollo, R.; Grün, D.; Trompouki, E.: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration. Nature Cell Biology 23, S. 704 - 717 (2021)

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publisher-version

publisher-version

Zeitschriftenartikel

Karoutas, A.; Akhtar, A.: Functional mechanisms and abnormalities of the nuclear lamina. Nature Cell Biology 23, S. 116 - 126 (2021)

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2020

Zeitschriftenartikel

Keller Valsecchi, C. I.; Basilicata, M. F.; Georgiev, P.; Gaub, A.; Seyfferth, J.; Kulkarni, T.; Panhale, A.; Semplicio, G.; Manjunath, V.; Holz, H. et al.; Dasmeh, P.; Akhtar, A.: RNA nucleation by MSL2 induces selective X chromosome compartmentalization. Nature 589, S. 137 - 142 (2020)

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Zeitschriftenartikel

Pessoa Rodrigues, C.; Shvedunova, M.; Akhtar, A.: Epigenetic Regulators as the Gatekeepers of Hematopoiesis. Trends in Genetics 37, S. 125 - 142 (2020)

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publisher-version

Zeitschriftenartikel

Samata, M.; Alexia, A.; Richard, G.; Georgiev, P.; Nuebler, J.; Kulkarni, T.; Renschler, G. V.; Basilicata, M. F.; Zenk, F. L.; Shvedunova, M. et al.; Semplicio, G.; Mirny, L.; Iovino, N.; Akhtar, A.: Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation. Cell 182, S. 127 - 144 (2020)

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Zeitschriftenartikel

Sheikh, B. N.; Guhathakurta, S.; Tsang, T. H.; Schwabenland, M.; Renschler, G. V.; Herquel, B.; Bhardwaj, V.; Holz, H.; Stehle, T.; Bondareva, O. et al.; Aizarni, N.; Mossad, O.; Kretz, O.; Reichardt, W.; Chatterjee, A.; Braun, L. J.; Thevenon, J.; Sartelet, H.; Blank, T.; Grün, D.; von Elverfeldt, D.; Huber, T. B.; Vestweber, D.; Avilov, S.; Prinz, M.; Büscher, J. M.; Akhtar, A.: Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nature Cell Biology 22, S. 828 - 841 (2020)

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Zeitschriftenartikel

Ilik, I. A.; Aktas, T.; Maticzka, D.; Backofen, R.; Akhtar, A.: FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucelic Acids Research 48, S. e15 (2020)

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Zeitschriftenartikel

Estrada Mallarino, L.; Engel, C.; Ilik, I. A.; Maticzka, D.; Heyl, F.; Müller, B.; Yakulov, T. A.; Dengjel, J.; Backofen, R.; Akhtar, A. et al.; Walz, G.: Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules. Scientific Reports 10, S. 1 - 14 (2020)

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Zeitschriftenartikel

Gaub, A.; Sheikh, B. N.; Basilicata, M. F.; Vincent, M.; Nizon, M.; Colson, C.; Bird, M. J.; Bradner, J. E.; Thevenon, J.; Boutros, M. et al.; Akhtar, A.: Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation. Nature Communications 11, S. 2243 (2020)

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Zeitschriftenartikel

Rodrigues, C. P.; Herman, J. S.; Herquel, B.; Velsecchi Keller, C. I.; Stehle, T.; Grün, D.; Akhtar, A.: Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Science Advances 6, S. eaaz4815 (2020)

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2019

Zeitschriftenartikel

Sheikh, B. N.; Bondareva, O.; Guhathakurta, S.; Tsang, T. H.; Sikora, K.; Aizarani, N.; Sagar, S.; Holz, H.; Grün, D.; Hein, L. et al.; Akhtar, A.: Systematic Identification of Cell-Cell Communication Networks in the Developing Brain. iScience 21, S. 273 - 287 (2019)

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Zeitschriftenartikel

Renschler, G.; Gautier, R.; Claudia, V.; Toscano, S.; Arrigoni, L.; Ramírez, F.; Akhtar, A.: Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling. Genes and Development 33, S. 1591 - 1612 (2019)

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Zeitschriftenartikel

Karoutas, A.; Szymanski, W. G.; Rausch, T.; Guhathakurta, S.; Rog-Zielinska, E. A.; Peyronnet, R.; Seyfferth, J.; Chen, H.-R.; de Leeuw, R.; Herquel, B. et al.; Kimura, H.; Mittler, G.; Kohl, P.; Medalia, O.; Korbel, J. O.; Akhtar, A.: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nature Cell Biology 21, S. 1248 - 1260 (2019)

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Zeitschriftenartikel

Bhardwaj, V.; Semplicio, G.; Erdogdu, N. U.; Manke, T.; Akhtar, A.: MapCap allows high-resolution detection and differential expression analysis of transcription start sites. Nature Communications 10, S. 3219 (2019)

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Zeitschriftenartikel

Panhale, A.; Richter , F. M.; Ramírez, F.; Shvedunova, M.; Manke, T.; Mittler, G.; Akhtar, A.: CAPRI enables comparison of evolutionary conserved RNA interacting regions. Nature Communications 10, 2682 (2019) (2019)

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Zeitschriftenartikel

Sheikh, B.; Guhathakurta, S.; Akhtar, A.: The non-specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis. EMBO Reports 20, S. e47360 (2019)

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