Publikationen von Thomas Boehm

Giorgetti, O. B.; Haas-Assenbaum, A.; Boehm, T.: Probing TCR Specificity Using Artificial In Vivo Diversification of CDR3 Regions. European Journal of Immunology 55, e202451434 (2024)

Boehm, T.: Understanding vertebrate immunity through comparative immunology. Nature Reviews Immunology 25, S. 141 - 152 (2024)

Lawir, D.-F.; Soza-Ried, C.; Iwanami, N.; Siamishi, I.; Bylund, G. O.; O'Meara, C.; Sikora, K.; Kanzler, B.; Johansson, E.; Schorpp, M. et al.; Cauchy, P.; Boehm, T.: Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. Communications Biology 7, 31 (2024)

Boehm, T.: The chilling origin of germinal centers. Science Immunology 8, eadl1470 (2023)

Das, S.; Boehm, T.; Holland, S. J.; Rast, J. P.; Fontenla-Iglesias, F.; Morimoto, R.; Valadez, J. G.; Heimroth, R. D.; Hirano, M.; Cooper, M. D.: Evolution of two distinct variable lymphocyte receptors in lampreys: VLRD and VLRE. Cell Reports 42, 112933 (2023)

Zhang, G.; Swann, J.; Felder, M.; O'Meara, C.; Boehm, T.: Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. European Journal of Immunology 53, e2350577 (2023)

Swann, J.; Grammer, C.; Schorpp, M.; Boehm, T.: A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons. BMC Immunology 24, 20 (2023)

Giorgetti, O. B.; O'Meara, C. P.; Schorpp, M.; Boehm, T.: Origin and evolutionary malleability of T cell receptor α diversity. Nature 619, S. 193 - 200 (2023)

Iwanami, N.; Richter, A. S.; Sikora, K.; Boehm, T.: Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells. Nature Communications 14, 3645 (2023)

Pircher, H.; Pinschewer, D. D.; Boehm, T.: MHC I tetramer staining tends to overestimate the number of functionally relevant self-reactive CD8 T cells in the pre-immune repertoire. European Journal of Immunology 53, 2350402 (2023)

Boehm, T.; Morimoto, R.; Trancoso, I.; Aleksandrova, N.: Genetic conflicts and the origin of self/nonself-discrimination in the vertebrate immune system. Trends in Immunology 44, S. 372 - 383 (2023)

Hess, I.; Sagar; Meara, C. O.; Grün, D.; Schorpp, M.; Boehm, T.: Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish. Scientific Reports 12, 21401 (2022)

Giorgetti, O. B.; Nusser, A.; Boehm, T.: Human thymoma-associated mutation of the GTF2I transcription factor impairs thymic epithelial progenitor differentiation in mice. Communications Biology 5, 1037 (2022)

Bayer, M.; Boller, S.; Ramamoothy, S.; Zolotarev, N.; Cauchy, P.; Iwanami, N.; Mittler, G.; Boehm, T.; Grosschedl, R.: Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling. Genes and Development 36, S. 901 - 915 (2022)

Iwanami, N.; Petersen, M.; Diekhoff, D.; Boehm, T.: Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding. Communications Biology 5, 911 (2022)

Nagakubo, D.; Hirakawa, M.; Iwanami, N.; Boehm, T.: Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. Scientific Reports 12, 13554 (2022)

Nusser, A.; Sagar; Swann, J.; Krauth, B.; Diekhoff, D.; Calderon, L.; Happe, C.; Grün, D.; Boehm, T.: Developmental dynamics of two bipotent thymic epithelial progenitor types. Nature 606, S. 165 - 171 (2022)

O’Meara, C. P.; Guerri, L.; Lawir, D.-F.; Mateos, F.; Iconomou, M.; Iwanami, N.; Soza-Ried, C.; Sikora, K.; Siamishi, I.; Giorgetti, O. B. et al.; Peter, S.; Schorpp, M.; Boehm, T.: Genetic landscape of T cells identifies synthetic lethality for T-ALL. Communications Biology 4, 1201 (2021)

Morimoto, R.; Swann, J.; Nusser, A.; Trancoso, I.; Schorpp, M.; Boehm, T.: Evolution of thymopoietic microenvironments. Open Biology 11, 200383 (2021)

Gahr, C. L.; Boehm, T.; Milinski, M.: Male validation factor for three-spined stickleback (Gasterosteus aculeatus) mate choice likely evolutionarily conserved since 50 thousand years. Ethology, Ecology & Evolution 33, S. 25 - 36 (2021)

Giorgetti, O. B.; Shingate, P.; O’Meara, C. P.; Ravi, V.; Pillai, N. E.; Tay, B.-H.; Prasad, A.; Iwanami, N.; Tan, H. H.; Schorpp, M. et al.; Venkatesh, B.; Boehm, T.: Antigen receptor repertoires of one of the smallest known vertebrates. Science Advances 7, eabd8180 (2021)

Swann, J.; Nusser, A.; Morimoto, R.; Nagakubo, D.; Boehm, T.: Retracing the evolutionary emergence of thymopoiesis. Science Advances 6, eabd9585 (2020)

Swann, J.; Holland, S. J.; Petersen, M.; Pietsch, T. W.; Boehm, T.: The immunogenetics of sexual parasitism. Science 369, S. 1608 - 1615 (2020)

Iwanami, N.; Lawir, D.-F.; Sikora, K.; Meara, C. O.; Takeshita, K.; Schorpp, M.; Boehm, T.: Transgenerational inheritance of impaired larval T cell development in zebrafish. Nature Communications 11, S. 4505 (2020)

Kury, P.; Führer, M.; Fuchs, S.; Lorenz, M. R.; Giorgetti, O. B.; Bakhtiar, S.; Frei, A. P.; Fisch, P.; Boehm, T.; Schwarz, K. et al.; Speckmann, C.; Ehl, S.: Long-term robustness of a T-cell system emerging from somatic rescue of a genetic block in T-cell development. EBioMedicine 59, 102961 (2020)

Trancoso, I.; Morimoto, R.; Boehm, T.: Co-evolution of mutagenic genome deditors and vertebrate adaptive immunity. Current Opinion in Immunology 65, S. 32 - 41 (2020)

Iwanami, N.; Takeshita, K.; Lawir, D.-F.; Suetake, I.; Tajima, S.; Sikora, K.; Trancoso, I.; O'Meara, C.; Siamishi, I.; Takahama, Y. et al.; Furutani-Seiki, M.; Kondoh, H.; Yonezawa, Y.; Schorpp, M.; Boehm, T.: Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience 23, 101260 (2020)

Lawir, D.-F.; Sikora, K.; O'Meara, C. P.; Schorpp, M.; Boehm, T.: Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development. Proceedings of the National Academy of Sciences of the United States of America 117, S. 15799 - 15808 (2020)

Siamishi, I.; Iwanami, N.; Clapes, T.; Trompouki, E.; O'Meara, C. P.; Boehm, T.: Lymphocyte-Specific Function of the DNA Plymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Reports 31, 107756 (2020)

Morimoto, R.; O’Meara, C. P.; Holland, S. J.; Trancoso, I.; Souissi, A.; Schorpp, M.; Vassaux, D.; Iwanami, N.; Giorgetti, O. B.; Evanno, G. et al.; Boehm, T.: Cytidine deaminase 2 is required for VLRB antibody gene assembly in lampreys. Science Immunology 5, eaba0925 (2020)